Monitoring kidney function biomarkers in transplant medicine
Biomarkers of Kidney Function in Transplant Medicine
University Hospital Ostrava · NCT05538234
This study is trying to see if new blood tests can help spot early signs of kidney problems in organ donors and recipients to improve transplant success.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Ostrava (other) |
| Locations | 1 site (Ostrava, Moravian-Silesian Region) |
| Trial ID | NCT05538234 on ClinicalTrials.gov |
What this trial studies
This observational study aims to monitor biomarkers of acute kidney dysfunction in deceased organ donors, living organ donors, and organ recipients. It involves collecting standard blood samples to assess kidney function without altering standard care practices. The study seeks to identify early signs of kidney impairment using sensitive tests, which could improve the criteria for organ acceptability and enhance transplant outcomes. Informed consent will be obtained from living donors and recipients.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older who are either living organ donors or recipients and meet the ethical and medical criteria for organ transplantation.
Not a fit: Patients who do not meet the legal or ethical requirements for organ harvesting or those whose family members disapprove of their participation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved kidney transplant outcomes by enabling the safe use of organs from marginal donors.
How similar studies have performed: Other studies have explored similar approaches to kidney function assessment, but the specific use of these biomarkers in transplant medicine is still being evaluated.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age 18+ * signed Informed Consent in case of living organ donors and recipients * fulfillment of all legal requirements for organ harvesting from a deceased donor * fulfillment of all ethical principles of end-of-life patient care * medical suitability of organs for transplant use Exclusion Criteria: - disapproval of family members with the enrolment of the patient in the study
Where this trial is running
Ostrava, Moravian-Silesian Region
- University Hospital Ostrava — Ostrava, Moravian-Silesian Region, Czechia (RECRUITING)
Study contacts
- Principal investigator: Peter Sklienka, MD, Ph.D. — University Hospital Ostrava
- Study coordinator: Jiří Hynčica
- Email: jiri.hyncica@fno.cz
- Phone: 0042059737
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Acute Kidney Injury, organ donor, organ recipient, transplant medicine, acute kidney injury