Monitoring intestinal blood flow after feeding to predict gut injury in critically ill patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will use bedside Doppler ultrasound to measure superior mesenteric artery (SMA) blood flow before and after enteral feeding in adult ICU patients. Investigators will record SMA flow changes alongside standard hemodynamic measurements and clinical markers of acute gastrointestinal injury (AGI). They will analyze patterns of SMA reactivity, develop a predictive model linking SMA changes to AGI risk, and explore how those findings could inform individualized enteral nutrition strategies. All data collection will occur in the ICU at Peking Union Medical College Hospital for patients who meet eligibility criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged ≥18 years and ≤80 years.
* Admitted to the study with a expected stay of more than 72 hours.
* Require initiation of enteral nutrition support.

Exclusion Criteria:

* Pre-existing severe gastrointestinal diseases.
* Patients with gastrointestinal bleeding.
* Patients with bowel obstruction.
* Pregnant or lactating women.
* Patients with contraindications to bedside Doppler ultrasound.

Where it's running

• Peking union medical college hospital
  Beijing, Beijing Municipality, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.