Monitoring internal jugular venous oxygen levels noninvasively

The Development of Novel Noninvasive Internal Jugular Venous Oximetry

National Taiwan University Hospital · NCT06004466

This study is testing a new device that can noninvasively monitor oxygen levels in the veins of cancer patients during major surgeries to improve their care and reduce risks from invasive procedures.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages20 Years to 70 Years
SexAll
SponsorNational Taiwan University Hospital (other)
Locations1 site (Taipei)
Trial IDNCT06004466 on ClinicalTrials.gov

What this trial studies

This study focuses on developing a novel plethysmographic monitoring device that aims to continuously measure internal jugular venous oxygen saturation without the need for invasive central venous catheter placement. By integrating ultrasound imaging with local tissue optical parameter estimation and considering individual tissue characteristics, the device seeks to provide real-time monitoring of oxygen levels in cancer patients undergoing major surgeries. This approach could potentially reduce the risks associated with invasive procedures while improving patient care through continuous monitoring.

Who should consider this trial

Good fit: Ideal candidates for this study are cancer patients who are scheduled to undergo major surgeries requiring central venous catheter placement.

Not a fit: Patients with signs of infection, impaired liver or renal function, or heart failure may not benefit from this study.

Why it matters

Potential benefit: If successful, this device could significantly enhance patient safety and monitoring capabilities during and after major cancer surgeries.

How similar studies have performed: While the approach of noninvasive monitoring is promising, it is relatively novel and has not been extensively tested in similar studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing major cancer surgery that requires central venous catheter placement
* Cancer patients undergoing totally implantable venous access device placement

Exclusion Criteria:

* Susepct infectious symptoms and signs (eg. white blood cell count count \>10000 ; fever \>38.3℃)
* impaired liver functions (aspartate aminotransferase\> 100 U/L); impaired renal function (estimated glomerular filtration rate \<60 mL/min/1.73 m2)
* heart failure, with New York Heart Associatation class 2 or more

Where this trial is running

Taipei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Neoplasms

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.