Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Monitoring fluid intake and weight gain after hemodialysis

Official title: Fluid Intake After Hemodialysis: Investigating the Relationship Between Time and Weight Gain During the Interdialytic Interval

Run by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · NCT04721652 · Data updated 2026-11-12

This study looks at how drinking fluids and gaining weight between dialysis sessions affects people who are on chronic hemodialysis.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment20 (estimated)
SponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Academic / other
Locations2 sites (London, Ontario and 1 other locations)
StatusRecruiting
StartedFebruary 25, 2021
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedMay 4, 2026
Trial IDNCT04721652 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who are on thrice weekly maintenance hemodialysis.

Probably not a fit

Patients with diabetes mellitus or significant residual urinary volume will not benefit from this study due to potential biases in thirst assessment.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the relationship between fluid intake and interdialytic weight gain in patients undergoing chronic hemodialysis. Approximately 20 participants will self-monitor their weight and blood pressure during the week between dialysis sessions. They will complete questionnaires and use medical-grade scales and blood pressure monitors to log their measurements four times daily. The study seeks to understand how fluid loss during hemodialysis affects thirst and subsequent fluid intake.

Why it matters

Potential benefit: If successful, this study could help optimize fluid management in hemodialysis patients, potentially reducing health risks associated with excessive weight gain.

How similar studies have gone: While the approach of monitoring fluid intake and weight gain is not widely tested, it builds on existing knowledge of fluid management in dialysis patients.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Thrice weekly maintenance hemodialysis
* Willing and able to provide written informed consent

Exclusion Criteria:

* Diabetes Mellitus
* Residual Urinary Volume \> 500 ml/day
* Being able to self-monitor one's body weight and blood pressure

Where it's running

  • Adam Linton Unit
    London, Ontario, Canada
    Recruiting
  • Westmount Kidney Care Centre
    London, Ontario, Canada
    Recruiting

Study contacts

  • Principal investigator: Christopher W. McIntyre, MD, PhD — London Health Sciences Centre, Western University
  • Study coordinator: Christopher W. McIntyre, MD, PhD
  • Email: cmcint48@uwo.ca
  • Phone: +1(519)685-8500

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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    This study tests whether taking pumpkin seed oil daily for 3 months helps reduce inflammation and improve-related lab markers in people with end-stage kidney disease on dialysis.

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  • Nurse-led self-care support to improve adherence and quality of life for people on hemodialysis

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  • How dialysis affects sexual function and intimacy

    This project will see how dialysis affects sexual health and intimacy in adults who have been on hemodialysis or peritoneal dialysis for at least six months.

    Recruiting CMC Ambroise Paré · Neuilly-sur-Seine, Île-de-France Region · NCT07332949

  • Using body composition and kidney function measurements to assess nutrition in hemodialysis patients

    This study is testing if using body composition and kidney function measurements can help better understand the nutrition of people on hemodialysis.

    Recruiting University of Tartu · Tartu, Tartu · NCT06873880

  • AP306 at fixed doses in adults on dialysis with high phosphate

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    Recruiting at 31 sites Phase 2 R1 Therapeutics · Huntsville, Alabama and 30 other locations · NCT06712654

  • Dialysis that removes more middle molecules using super high‑flux filters

    This trial will test whether using super high‑flux (expanded) dialysis filters instead of standard high‑flux filters reduces the risk of death and other harms for adults on in‑center hemodialysis who are older or have diabetes.

    Recruiting at 2 sites London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario and 2 other locations · NCT06660277

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.