Monitoring fluid intake and weight gain after hemodialysis
Official title: Fluid Intake After Hemodialysis: Investigating the Relationship Between Time and Weight Gain During the Interdialytic Interval
Run by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · NCT04721652 · Data updated 2026-11-12
This study looks at how drinking fluids and gaining weight between dialysis sessions affects people who are on chronic hemodialysis.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 20 (estimated) |
| Sponsor | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Academic / other |
| Locations | 2 sites (London, Ontario and 1 other locations) |
| Status | Recruiting |
| Started | February 25, 2021 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | May 4, 2026 |
| Trial ID | NCT04721652 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who are on thrice weekly maintenance hemodialysis.
✕Probably not a fit
Patients with diabetes mellitus or significant residual urinary volume will not benefit from this study due to potential biases in thirst assessment.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the relationship between fluid intake and interdialytic weight gain in patients undergoing chronic hemodialysis. Approximately 20 participants will self-monitor their weight and blood pressure during the week between dialysis sessions. They will complete questionnaires and use medical-grade scales and blood pressure monitors to log their measurements four times daily. The study seeks to understand how fluid loss during hemodialysis affects thirst and subsequent fluid intake.
Why it matters
Potential benefit: If successful, this study could help optimize fluid management in hemodialysis patients, potentially reducing health risks associated with excessive weight gain.
How similar studies have gone: While the approach of monitoring fluid intake and weight gain is not widely tested, it builds on existing knowledge of fluid management in dialysis patients.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Thrice weekly maintenance hemodialysis * Willing and able to provide written informed consent Exclusion Criteria: * Diabetes Mellitus * Residual Urinary Volume \> 500 ml/day * Being able to self-monitor one's body weight and blood pressure
Where it's running
-
Adam Linton Unit
London, Ontario, Canada Recruiting -
Westmount Kidney Care Centre
London, Ontario, Canada Recruiting
Study contacts
- Principal investigator: Christopher W. McIntyre, MD, PhD — London Health Sciences Centre, Western University
- Study coordinator: Christopher W. McIntyre, MD, PhD
- Email: cmcint48@uwo.ca
- Phone: +1(519)685-8500
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Pumpkin seed oil for people on hemodialysis
This study tests whether taking pumpkin seed oil daily for 3 months helps reduce inflammation and improve-related lab markers in people with end-stage kidney disease on dialysis.
-
Nurse-led self-care support to improve adherence and quality of life for people on hemodialysis
A nurse-led program using laptop-based education, reminders, and a self-care booklet will be tested to see if it helps adults on hemodialysis better follow diet and fluid rules and feel their best.
-
How dialysis affects sexual function and intimacy
This project will see how dialysis affects sexual health and intimacy in adults who have been on hemodialysis or peritoneal dialysis for at least six months.
-
Using body composition and kidney function measurements to assess nutrition in hemodialysis patients
This study is testing if using body composition and kidney function measurements can help better understand the nutrition of people on hemodialysis.
-
AP306 at fixed doses in adults on dialysis with high phosphate
This trial tests if AP306, taken daily at different doses, can safely lower phosphate levels in adults on maintenance dialysis with hyperphosphatemia.
-
Dialysis that removes more middle molecules using super high‑flux filters
This trial will test whether using super high‑flux (expanded) dialysis filters instead of standard high‑flux filters reduces the risk of death and other harms for adults on in‑center hemodialysis who are older or have diabetes.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.