Monitoring brain injury during neurosurgery
Electrocorticography As a Neurophysiological Marker for Intraoperative Monitoring for Brain Retraction: an IDEAL Stage 1 Study
This study is testing if a new way to monitor brain health during surgery can help protect adults from injuries caused by brain retraction.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 6 (estimated) |
| Ages | 16 Years and up |
| Sex | All |
| Sponsor | University College, London Academic / other |
| Locations | 1 site (London, Greater London) |
| Trial ID | NCT06409806 on ClinicalTrials.gov |
What this trial studies
This study investigates the feasibility of using electrocorticographic (ECOG) monitoring to detect brain retraction injury in adult patients undergoing neurosurgery. Participants will have an ECOG electrode placed on the brain during their standard surgical procedure to monitor for potential injury caused by brain retraction. This is the first human study of its kind, building on previous preclinical findings in mice. The goal is to enhance patient safety and surgical outcomes by providing real-time data on brain health during surgery.
Who should consider this trial
Good fit: Ideal candidates are adults aged 16 or older who are scheduled for intracranial surgery involving fixed brain retraction.
Not a fit: Patients who lack the capacity to give consent at the time of recruitment will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved monitoring and prevention of brain injury during neurosurgical procedures.
How similar studies have performed: While this approach is novel and has not been tested in humans before, previous preclinical studies in mice have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 16 or older undergoing intracranial surgery where it is anticipated fixed brain retraction will be used. Exclusion Criteria: * Patients without capacity to give consent at time of recruitment
Where this trial is running
London, Greater London
- National Hospital Neurology and Neurosurgery — London, Greater London, United Kingdom (Recruiting)
Study contacts
- Study coordinator: Siddharth Sinha
- Email: siddharth.sinha@ucl.ac.uk
- Phone: 004420 3456 7890
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.