Monitoring brain damage in patients after cardiac arrest
Assessment of Brain Damage Using Monitoring of Cerebral Oximetry Dynamics in Patients After Cardiac Arrest
This study is testing a way to monitor brain damage in unconscious patients who have survived a cardiac arrest to see if improving blood flow to the brain can help them recover better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Medical Centre Maribor Academic / other |
| Locations | 1 site (Maribor) |
| Trial ID | NCT06776302 on ClinicalTrials.gov |
What this trial studies
This study aims to assess brain damage in patients who have experienced a cardiac arrest by monitoring cerebral oximetry dynamics. It focuses on patients who are unconscious after regaining spontaneous circulation and evaluates the potential for improved blood flow to the brain as a treatment intervention. The study employs a multimodal approach to predict neurological outcomes, integrating clinical examinations and various diagnostic tools. The goal is to enhance the understanding of brain recovery post-cardiac arrest and improve patient management in intensive care settings.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who have suffered a primary out-of-hospital cardiac arrest and are unconscious after regaining spontaneous circulation.
Not a fit: Patients with conditions such as intracranial hemorrhage, hypothermia, or those defined as palliative or terminal may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better prognostic assessments and improved outcomes for patients recovering from cardiac arrest.
How similar studies have performed: While the approach of using cerebral oximetry is gaining interest, the specific methodology of this study is relatively novel and has not been extensively tested in similar contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age over 18 years * Primary out-of-hospital cardiac arrest * Unconsciousness after return of spontaneous circulation (8 points or less on the Glasgow Coma Scale) Exclusion Criteria: * Intracranial hemorrhage (clinically suspected or proven by CT scan) * Hypothermia (body temperature less than 32 degrees Celsius) * Pregnancy * Uncontrollable bleeding * Uncontrollable blood pressure fluctuations * Patient defined as palliative or terminal * Cardiac arrest secondary to drowning, hypothermia, or trauma
Where this trial is running
Maribor
- University clinical center Maribor — Maribor, Slovenia (Recruiting)
Study contacts
- Study coordinator: Rok Petrovčič, MD
- Email: rok.5rovcic@gmail.com
- Phone: +38631215650
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.