Monitoring blood pressure changes during pregnancy in women who used assisted reproductive technology
The Trajectory of Blood Pressure During Pregnancy in Assisted Reproductive Females
The Second Hospital of Shandong University · NCT06426732
This study looks at how blood pressure changes during pregnancy in women who used assisted reproductive technology compared to those who got pregnant naturally to see if there are any risks for high blood pressure.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 20 Years to 45 Years |
| Sex | Female |
| Sponsor | The Second Hospital of Shandong University (other) |
| Locations | 1 site (Jinan) |
| Trial ID | NCT06426732 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the blood pressure trajectory in women who conceive through assisted reproductive technology (ART) compared to those who conceive naturally. It aims to identify risk factors associated with elevated blood pressure during pregnancy in the ART population by continuously monitoring their blood pressure and other relevant factors. The study establishes a prospective cohort of both ART and natural pregnancy groups to explore trends and potential intervention points for managing hypertension-related risks during pregnancy.
Who should consider this trial
Good fit: Ideal candidates include women who have undergone at least one cycle of IVF or ICSI and achieved clinical pregnancy, as well as women who conceived naturally.
Not a fit: Patients who have pre-existing hypertension, hereditary diseases, or other significant health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management and prevention strategies for hypertension in pregnant women who used assisted reproductive technology.
How similar studies have performed: While there is existing research on hypertension in pregnancy, this specific focus on ART populations is relatively novel and may provide new insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: -Exposure group: Mother: Seen in the obstetrics department of our hospital and meet the following conditions at the same time: 1. Complete at least one cycle of IVF or ICSI, PGD or IVM treatment (including natural cycles); 2. Clinical pregnancy was obtained after treatment. Offspring: Offspring born after in vitro fertilization-embryo transfer technique. * Non-exposed group: Mother: A mother who conceived naturally. Offspring: 1) Offspring born by natural pregnancy. 2) Offspring born from natural pregnancy of exposed mothers. Exclusion Criteria: * Unwilling to participate in this research; * Unable to participate in this study due to special reasons, such as death, immigration, loss to follow-up; * Hereditary diseases, mental diseases, malignant tumors, pre-pregnancy hypertension, uterine malformations and other reproductive organ malformations; * Pregnant women who voluntarily terminate pregnancy due to non-preeclampsia factors;
Where this trial is running
Jinan
- Cui linlin — Jinan, China (RECRUITING)
Study contacts
- Study coordinator: Wenting Wang, M.D. Ph.D.
- Email: 13188936075@163.com
- Phone: +86 17660082326
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Blood Pressure