Monitoring blood flow changes during heart surgery
Blood Velocity Variation in Right Renal and Superior Mesenteric Arteries During Cardio-pulmonary Bypass
This study looks at how blood flow changes in certain arteries during heart surgery to see if it affects kidney health and could help improve surgical care.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 92 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 1 site (Roma) |
| Trial ID | NCT06009809 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the variations in blood velocity in the right renal and superior mesenteric arteries during cardiopulmonary bypass (CPB) in cardiac surgery. It aims to understand the impact of CPB on organ perfusion, particularly focusing on the risk of acute kidney injury (AKI) and its associated complications. By utilizing transesophageal echocardiography, the study will assess how different blood flow patterns during surgery may contribute to renal hypoperfusion and subsequent organ damage. The findings could provide insights into improving surgical techniques and patient outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years undergoing cardiac surgery with cardiopulmonary bypass and with preoperative serum creatinine levels below 1.2 mg/dl.
Not a fit: Patients with contraindications to transesophageal echocardiography or those with severe preoperative renal impairment or emergency surgery may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better management strategies during heart surgery, potentially reducing the incidence of acute kidney injury.
How similar studies have performed: While the specific approach of this study may be novel, previous studies have indicated that monitoring blood flow during cardiac surgery can provide valuable insights into preventing organ damage.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * age\> 18 years * written informed consent * cardiac surgery with cardiopulmonary bypass (CPB) * New York Heart Association (NYHA) class I, II, III * preoperative serum creatinine less than 1.2 mg / dl Exclusion Criteria: * contraindications to Trans Esophageal Ultrasound (TEE) based on American Society of Anesthesiologists (ASA) recommendations (esophageal or gastric diseases or previous surgery) * history of non-coronary arterial pathologies * atrial fibrillation * preoperative serum creatinine greater than 1.2 mg / dl • NYHA class IV * emergency cardiac surgery
Where this trial is running
Roma
- Fondazione Policlinico Universitario A,Gemelli IRCCS — Roma, Italy (Recruiting)
Study contacts
- Study coordinator: Gabriella Arlotta, M.D.
- Email: g.arlotta72@gmail.com
- Phone: +390630154848
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.