Monitoring and managing nighttime high blood pressure
Official title: Registry Study on "Control Nocturnal Hypertension to Reach the Target "（CONTROL-NHT）
Run by Shanghai Institute of Hypertension · NCT04137549 · Data updated 2026-11-12
This study is testing how monitoring nighttime blood pressure can help people aged 50-79 with high blood pressure manage their condition better and reduce their risk of heart problems.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 50 Years to 79 Years |
| Sex | All |
| Enrollment | 4500 (estimated) |
| Sponsor | Shanghai Institute of Hypertension Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | December 1, 2019 |
| Main results expected | September 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | January 6, 2025 |
| Trial ID | NCT04137549 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 50-79 with diagnosed hypertension who are currently taking antihypertensive medications and have elevated nocturnal blood pressure.
✕Probably not a fit
Patients who do not use antihypertensive drugs or those who are hospitalized for hypertension may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on patients aged 50-79 with diagnosed hypertension who are using antihypertensive medications. It aims to monitor nocturnal blood pressure using ambulatory blood pressure monitoring (ABPM) to identify and manage nocturnal hypertension, which is linked to increased cardiovascular risks. The study emphasizes the importance of controlling blood pressure during nighttime to potentially reduce the risk of serious cardiovascular events. Participants will provide information about their medical history and undergo blood biochemical tests.
Why it matters
Potential benefit: If successful, this study could lead to improved management of nocturnal hypertension, reducing the risk of cardiovascular events in patients.
How similar studies have gone: Other studies have shown that monitoring nocturnal blood pressure can provide valuable insights into cardiovascular risk, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 50-79 years old * Clinical diagnosed hypertension with the use of antihypertensive drugs * Nocturnal hypertension ( nocturnal systolic blood pressure ≥ 130 mmHg and/or nocturnal diastolic blood pressure ≥ 80 mmHg) * A 24-hour ambulatory blood pressure monitoring was performed with validated equipment. * Willing to provide information about disease history and blood biochemical test data within 6 months. * Sign the informed consent Exclusion Criteria: * Without antihypertensive drug use * Hospitalized hypertension patients * Non-compliant patient
Where it's running
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Ruijin Hospital
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Study coordinator: Yan Li, MD,PhD
- Email: liyanshcn@163.com
- Phone: 0086-021-64370045
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Lowering home blood pressure targets for elderly patients
This study tests if lowering the home blood pressure target for older adults can help prevent heart problems and improve their health.
-
Comparing morning and bedtime dosing of blood pressure medication
This study is testing whether taking blood pressure medication in the morning or at bedtime works better to lower blood pressure in people with high blood pressure who haven't been treated before.
-
Registry on controlling blood pressure in ten thousand patients
This study is testing how well 24-hour blood pressure monitoring can help people with high blood pressure manage their condition and improve their heart health.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.