Modified TLIP vs Retrolaminar block for pain after two-level lumbar spine surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, randomized, double-blind study compares two regional anesthesia techniques—modified Thoracolumbar Interfascial Plane (mTLIP) block and Retrolaminar block—for managing postoperative pain in adults undergoing elective two-level lumbar spine procedures. The primary outcome is total morphine consumption in the first 24 hours after surgery. Secondary outcomes include pain scores, time to first rescue analgesia, block performance metrics, side effects, functional recovery, and patient satisfaction. Local anesthetic is administered with adjuncts and the approach targets dorsal rami to reduce opioid needs while facilitating recovery. The trial will help determine which block offers more effective analgesia with potentially fewer opioid-related adverse effects.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 21 and 65 years
* ASA physical status I or II
* BMI \< 30 kg/m²
* Scheduled for elective two-level lumbar spine surgery (discectomy/decompression)
* Expected duration of surgery less than 3 hours
* Patient's acceptance and written informed consent

Exclusion Criteria:

* Infection at block site
* Known allergy to used drugs
* Coagulation disorder
* History of psychiatric illness
* Pre-existing neurological deficits
* Presence of any metastasis
* Previous lumbar spine surgeries
* Patients on previous opioid therapy

Where it's running

• Zagazig University Hospitals, Anesthesia, Intensive Care and Pain Management Department
  Zagazig, Sharqia Province, Egypt Recruiting

Study contacts

• Principal investigator: Mohamed Shehta Mohamed Ali, M.B.B.CH — Zagazig University
• Study coordinator: Mohamed Shehta Mohamed Ali
• Email: m.shehta025@medicine.zu.edu.eg
• Phone: +2001014634299

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.