Clinical trial Recruiting at 1 site Interventional Ages 18 to 45

Moderate-load eccentric core exercises versus Pilates for adults with non-specific low back pain

Official title: Comparison of Moderate Load Eccentric Core Exercises and Pilates in Patients With Non-Specific Low Back Pain

Run by Foundation University Islamabad · NCT07332390 · Data updated 2026-11-12

This project will test whether moderate-load eccentric core exercises or Pilates work better to reduce pain and improve function in adults 18–45 with chronic non-specific low back pain.

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexAll
Enrollment44 (estimated)
SponsorFoundation University Islamabad
Academic / other
Locations1 site (Islamabad, Punjab Province)
StatusRecruiting
StartedJanuary 15, 2025
Main results expectedDecember 31, 2025
Study endsJanuary 15, 2026
Registry record updatedJanuary 12, 2026
Trial IDNCT07332390 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults 18–45 years old with non-specific low back pain for more than three months and pain rated 3–8 on the numeric pain rating scale, without neurological signs or major spinal pathology.

Probably not a fit

People with radicular leg symptoms, clear structural spinal disease (e.g., spondylolisthesis, significant scoliosis), recent abdominal/spinal/lower limb surgery, pregnancy, or very severe acute pain (NPRS >8) are unlikely to benefit from this program and are excluded.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults aged 18–45 with non-specific low back pain lasting more than three months are assigned to either a supervised program of moderate-load eccentric core exercises or a supervised Pilates program. Outcomes measured before and after the intervention include pain intensity, joint position error (proprioception), lumbar range of motion, and core muscle endurance. Participants with radicular symptoms, structural spinal disease, recent surgery, pregnancy, or very severe acute pain are excluded. The comparison aims to determine which exercise approach better restores neuromuscular control and reduces persistent pain.

Why it matters

Potential benefit: If successful, one of these exercise programs could offer a practical, non-surgical way to reduce pain, improve core control and proprioception, and lower the chance of recurrent low back pain.

How similar studies have gone: Pilates has shown modest benefit for chronic low back pain in prior trials, while moderate-load eccentric core training is less well-studied and supported mainly by smaller or mechanistic studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Adults 18 to 45 years

  * Both genders
  * Low back (from T12 to buttock line) pain for more than 3 months
  * Non-specific low back pain i.e. signs or symptoms not attributable to any specific structure
  * Low back pain on 3-8 NPRS

Exclusion Criteria:

* • Acute flare Low Back Pain

  * Low back pain on NPRS (\>8)
  * Thoracic pain
  * Centralization and peripheralization of pain
  * Leg symptoms when walking, eased in flexion (Signs of stenosis)
  * Pain due to repetitive movement
  * Paresthesia/numbness
  * Structural deformity (scoliosis, spondylosis, spondylolisthesis)
  * Curve reversal
  * Pregnancy
  * Post-surgery (within 6 months of abdominal, spinal, or lower limb surgery)
  * Degenerative or inflammatory spinal diseases
  * Malignancy

Where it's running

  • Foundation University Islamabad
    Islamabad, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.