Modeling muscle strength in patients with motor impairments
Study for the Development and Evaluation of Personalised Muscle Effort Generation Models for Patients With Upper Limb Motor Deficits
This study is trying to understand how people with upper limb motor impairments can use their muscles by measuring their strength at different speeds and angles to help improve rehabilitation and robotic assistance.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | Pôle Saint Hélier Academic / other |
| Locations | 1 site (Rennes) |
| Trial ID | NCT06608121 on ClinicalTrials.gov |
What this trial studies
This study focuses on developing mathematical models to describe the residual muscle forces in patients with upper limb motor impairments caused by conditions such as stroke, multiple sclerosis, and spinal cord injuries. By measuring upper limb isokinetic forces, the study aims to understand how these patients can generate voluntary muscle force depending on joint angle and motion speed. The findings could inform rehabilitation strategies and assist in creating robotic systems that adapt to the patients' remaining capabilities.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 85 with motor deficits due to stroke, multiple sclerosis, or spinal cord injuries.
Not a fit: Patients with severe spasticity, cognitive impairments, or other significant health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance rehabilitation techniques and improve the quality of life for patients with motor impairments.
How similar studies have performed: While similar approaches have been explored, this specific modeling of muscle strength in impaired patients is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged between 18 and 85 * A patient who is a member or beneficiary of a social security scheme * Patients hospitalised at the Saint-Hélier rehabilitation centre for a stroke more than 15 days old, MS or SCI * Patients with a motor deficit ≤3/5 on the MRC (Medical Research Council) scale in both internal-external shoulder rotation and elbow flexion-extension. * Patient with voluntary consent to participate in this study. Exclusion Criteria: * Spasticity \>3/4 on the Aschworth scale in the shoulder abductor or elbow flexor muscles. * Cognitive impairment that may interfere with measurements (MOCA \< 20/30) * Presence of a pressure sore \> stage 2 at the ischial level * Recent trauma to limbs or spine * Decompensated heart disease or other unbalanced pathology which contraindicates or may hinder isokinetic testing. * Persons deprived of their liberty by a judicial or administrative decision * Pregnant women, women in labour or nursing mothers.
Where this trial is running
Rennes
- Fondation Saint-Hélier — Rennes, France (Recruiting)
Study contacts
- Study coordinator: Emilie LEBLONG, MD
- Email: emilie.leblong@fondationsainthelier.com
- Phone: +33299295099
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.