Mobile app for cognitive behavioral therapy in stroke recovery

Mobile Cognitive Behavioral Therapy for Stroke

Not applicable Interventional Weill Medical College of Cornell University · NCT06689878

This study tests a mobile app called 'MAYA' to see if it can help adults recovering from a stroke manage anxiety and depression through cognitive behavioral therapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment10 (estimated)
Ages40 Years to 79 Years
SexAll
SponsorWeill Medical College of Cornell University Academic / other
Locations1 site (New York, New York)
Trial IDNCT06689878 on ClinicalTrials.gov

What this trial studies

This study evaluates the feasibility and acceptability of 'MAYA', a mobile cognitive behavioral therapy app designed for adults who have experienced a stroke. Participants will use the app for at least two days a week over an 8-week period, with weekly check-ins to monitor adherence and mood symptoms. The study will assess the number of sessions completed and gather qualitative feedback, as well as preliminary efficacy on anxiety and depression symptoms using standardized measures.

Who should consider this trial

Good fit: Ideal candidates are adults aged 40-79 who have experienced a stroke at least one month prior and have clinically significant anxiety or depression.

Not a fit: Patients with moderate to severe aphasia, active suicidal ideation, or those currently engaged in psychotherapy focused on CBT may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could improve mental health outcomes for stroke survivors dealing with anxiety and depression.

How similar studies have performed: Other studies have shown promise in using mobile CBT applications for mental health, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 40-79
* Presence of clinically-significant anxiety and/or depression (as determined by an eligibility evaluation)
* Stroke that occurred 1 month or more prior to study initiation
* Capacity to provide consent
* No greater than mild cognitive difficulties based on an eligibility evaluation conducted as part of the study
* If taking medication for depression and/or anxiety, must be on a stable dose for a minimum of 8 weeks prior to study initiation
* Ability to use iPhone or iPad independently
* Home internet access
* Willingness to participate in the full study duration.

Exclusion Criteria:

* Aphasia of moderate or greater severity (as determined during an eligibility evaluation)
* Non-fluency in English
* History of a bipolar or psychotic disorder
* Current alcohol or substance use disorder
* Active suicidal ideation
* Current engagement in psychotherapy is not grounds for exclusion unless the individual's psychotherapy is primarily focused on CBT
* Severe depression and/or anxiety based on the initial evaluation and clinical judgment of the study doctor, which warrants a higher level of care and/or immediate referral to psychiatric services
* Any other clinical or medical reason in the study doctor's initial screening evaluation that suggests the study is not appropriate for the participant

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AnxietyStrokeDepressionstroke recoverystroke rehabilitationcognitive behavioral therapyCBT
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.