Mir Shakeel teleintegrated therapy for recovery after total knee replacement
The Effects of Mir Shakeel Teleintegrated Therapy Plan and Conventional Physical Therapy on Pain, Range of Motion, Gait, Functional Outcomes and Quality of Life in Patients Undergoing Total Knee Arthroplasty
This trial will test whether a structured telerehabilitation program (MSTITP) helps people aged 50–65 recover better after primary total knee replacement compared with standard in-person physiotherapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 50 Years to 65 Years |
| Sex | All |
| Sponsor | Lincoln University College Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Trial ID | NCT07239258 on ClinicalTrials.gov |
What this trial studies
This two-arm, parallel-group randomized controlled trial will randomly assign adults aged 50–65 who had primary unilateral TKA to either a telerehabilitation program (MSTITP) or conventional face-to-face physiotherapy. The MSTITP arm delivers supervised video sessions, home-based progressive strengthening and range-of-motion exercises, gait re-education, and regular remote monitoring, while the control arm receives equal-duration clinic-based physiotherapy targeting the same outcomes. Primary outcomes include pain, range of motion, gait and functional mobility, with secondary measures of adherence and quality of life assessed at predefined follow-up points. Participants will be recruited and followed at Ghurki Trust and Teaching Hospital in Lahore and must have internet-capable devices for the telerehabilitation arm.
Who should consider this trial
Good fit: Ideal candidates are adults 50–65 who underwent a primary unilateral TKA for osteoarthritis, are medically stable for rehabilitation, and have reliable internet access and a device for video sessions.
Not a fit: Patients with prior knee replacement or revision surgery, significant comorbidities or neurological conditions that limit safe exercise, or those without reliable internet or the ability to use video calls are unlikely to benefit from the telerehabilitation arm.
Why it matters
Potential benefit: If successful, the telerehabilitation program could improve access and adherence while producing similar or better pain relief, range of motion, gait, and functional outcomes compared with standard physiotherapy.
How similar studies have performed: Previous randomized trials and systematic reviews have shown telerehabilitation after TKA can be non-inferior to in-person physiotherapy for pain and function, but protocols and results have been variable.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who have underwent a primary unilateral total knee arthroplasty due to osteoarthritis * Able to participate in a rehabilitation program, either telerehabilitation or in-person, and demonstrate sufficient mobility with or without assistive devices (e.g., crutches, walker) as deemed appropriate for post-TKA therapy. * Participants must have reliable access to a smartphone, tablet, or computer with internet connectivity and the ability to engage in video calls. * Willing and able to provide informed consent, and to comply with all study protocols, including scheduled therapy sessions and follow-up assessments. Exclusion Criteria: * Presence of significant comorbidities or complications that could interfere with safe participation in rehabilitation, such as severe cardiovascular disease, or conditions causing significant immobility (e.g., severe osteoarthritis in other joints or Rheumatoid Arthritis. * Previous knee replacement or other significant knee surgeries on the same knee, as this may impact the standardization of rehabilitation outcomes. * Currently enrolled in another physical therapy or rehabilitation trial, or engaging in additional rehabilitation outside the study protocol. * Cognitive impairment or severe visual or hearing impairments that would prevent them from following therapy instructions or engaging with telerehabilitation technology. * Any other conditions or factors that, in the opinion of the investigators, could hinder compliance with the study procedures or put the participant at undue risk.
Where this trial is running
Lahore, Punjab Province
- Ghurki Trust and Teaching Hospital — Lahore, Punjab Province, Pakistan (Recruiting)
Study contacts
- Principal investigator: Dr. Mir Shakeel Ahmad — Lincoln College University
- Study coordinator: Dr. Mir Shakeel Ahmad
- Email: mirshakeel.phdscholar@lincoln.edu.my
- Phone: 00923224268894
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.