Minimally invasive gum treatment using Emdogain® MI
The Use of a Non-Incised Minimally Invasive Flap Procedure in Conjunction With Emdogain® MI Compared to Traditional SRCP
This study is testing a new, less invasive gum treatment using Emdogain® MI to see if it works better than traditional cleaning methods for people with gum disease.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 32 (estimated) |
| Ages | 30 Years to 75 Years |
| Sex | All |
| Sponsor | Texas A&M University Academic / other |
| Locations | 1 site (Dallas, Texas) |
| Trial ID | NCT05964699 on ClinicalTrials.gov |
What this trial studies
This study evaluates a non-incised minimally invasive flap procedure combined with Emdogain® MI for treating periodontitis and attachment loss. The approach involves removing a portion of the sulcus lining through curettage, allowing for better visualization and debridement of the root surface using a videoscope. Participants will be compared against those receiving traditional scaling and root planing to assess the effectiveness of this innovative technique. The goal is to improve outcomes in periodontal therapy by utilizing a less invasive method.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 30 to 75 with generalized gum disease and specific pocket depths and attachment loss.
Not a fit: Patients who are pregnant, breastfeeding, or have serious medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved healing and attachment in patients with gum disease.
How similar studies have performed: While similar minimally invasive approaches have shown mixed success, this specific modification is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: To participate in this study, you must present: * Generalized gum disease with isolated pocket depths of 5 mm to less than 7 mm on bicuspid and cuspid teeth. * At least 2 mm of attachment loss. * Need to have two similar teeth meeting the criteria for isolated pockets on two other quadrants of the mouth. * Need to be between 30 and 75 years of age. * Be in good health. * Smoke less than 10 cigarettes or equivalent per day. * No antibiotics for the past 90 days. * Not be taking medications that are known to inhibit or slow healing. Exclusion Criteria: You are not eligible if: * You are pregnant. * You are breast feeding. * Received gum treatment in the last 6 months. * Smoke more than ten cigarettes per day. * You have any serious medical conditions.
Where this trial is running
Dallas, Texas
- Texas A&M School of Dentistry — Dallas, Texas, United States (Recruiting)
Study contacts
- Study coordinator: Daniel Patrick O Ryan, DDS
- Email: dryan@tamu.edu
- Phone: 2143642857
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.