Mindfulness intervention to prevent chemo-brain in women with breast cancer
Pilot Feasibility Evaluation of a Mindfulness (Mindfulness) Intervention in Women Preparing for Chemotherapy for Breast Cancer
This study is testing if an 8-week mindfulness program can help women with breast cancer avoid memory and thinking problems while they prepare for chemotherapy.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 12 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Thomas Jefferson University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Philadelphia, Pennsylvania) |
| Trial ID | NCT06219434 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of an 8-week mindfulness intervention aimed at preventing cognitive dysfunction, commonly referred to as chemo-brain, in women preparing for chemotherapy for breast cancer. Participants will engage in mindfulness practices that include breathing exercises, mindful eating, and awareness techniques over 2.5 hours weekly. The study will also assess cognitive function, quality of life, and brain imaging through fMRI, alongside blood sample collection to explore related factors. Follow-up assessments will occur three months after the intervention to evaluate long-term effects.
Who should consider this trial
Good fit: Ideal candidates are women aged 18 and older who have been diagnosed with breast cancer and are preparing to undergo chemotherapy.
Not a fit: Patients under 18 or those unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce cognitive dysfunction in women undergoing chemotherapy for breast cancer, improving their quality of life.
How similar studies have performed: While mindfulness interventions have shown promise in various settings, this specific approach to preventing chemo-brain is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years or older * Breast cancer diagnosis preparing to undergo chemotherapy Exclusion Criteria: * Under the age of 18 * Cannot provide informed consent
Where this trial is running
Philadelphia, Pennsylvania
- Thomas Jefferson University Hopsital — Philadelphia, Pennsylvania, United States (Recruiting)
Study contacts
- Study coordinator: Ana maria Lopez, MD
- Email: AnaMaria.Lopez@jefferson.edu
- Phone: 215-503-7917
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.