Mindful self-compassion program for unhoused women with PTSD and substance use issues

Mindful Self-Compassion to Address PTSD and Substance Use in Unhoused Women

NA · University of California, Los Angeles · NCT06646692

This study is testing a mindful self-compassion program to see if it can help homeless women with PTSD and substance use issues feel better and improve their lives.

Quick facts

PhaseNA
Study typeInterventional
Enrollment202 (estimated)
Ages18 Years and up
SexFemale
SponsorUniversity of California, Los Angeles (other)
Locations1 site (Pomona, California)
Trial IDNCT06646692 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of a mindful self-compassion intervention for women experiencing homelessness who are dealing with posttraumatic stress disorder (PTSD) and substance use disorder (SUD). The approach combines mindful self-compassion techniques with standard treatment practices to address the complex interplay of trauma, mental health, and substance use. Participants will be women aged 18 and over who have experienced homelessness and exhibit symptoms of PTSD. The study seeks to provide a low-cost, complementary intervention to improve mental health outcomes and reduce substance use among this vulnerable population.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 18 and over who have experienced homelessness and exhibit probable PTSD symptoms.

Not a fit: Patients who do not speak English or have cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve mental health and reduce substance use among unhoused women suffering from PTSD.

How similar studies have performed: Other studies have shown promise in using mindfulness-based interventions for PTSD and substance use, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Identifies as woman
* Age 18 and over
* Probable PTSD as judged by the PCL-5 (score of 31 or higher, indicated as having optimal signal detection)
* No cognitive impairment according to a score of \< 10 on the Short-Blessed Test
* Experienced homelessness in the past 6 months or prior to incarceration ("spent night in public or private shelter or on the street")
* Able to speak and understand English.

Exclusion Criteria:

* Not able to speak English
* Judged to be cognitively impaired, as indicated by score \> 10 on the Short-Blessed Screener
* Does not meet other inclusion criteria

Where this trial is running

Pomona, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Posttraumatic Stress Disorder, Anxiety, Depression - Major Depressive Disorder, homelessness, mindful self compassion, depression, substance use disorder, craving

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.