Methionine availability from tempeh chips in reproductive-age women
Official title: Understanding the Metabolic Availability of Methionine in High Calcium Tempeh (TempeCalTM) Chips Among Reproductive-Age Women by Using the Stable Isotope Technique
Run by National University of Malaysia · NCT07251842 · Data updated 2026-11-12
This study tests how much methionine from tempeh chips is usable by healthy women of childbearing age, using a stable isotope method.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 19 Years to 30 Years |
| Sex | Women only |
| Enrollment | 6 (estimated) |
| Sponsor | National University of Malaysia Academic / other |
| Locations | 1 site (Kuala Lumpur) |
| Status | Recruiting |
| Started | October 20, 2026 |
| Main results expected | March 15, 2027 |
| Study ends | May 20, 2027 |
| Registry record updated | August 5, 2026 |
| Trial ID | NCT07251842 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are Malaysian women aged 19–30 who are healthy, have stable weight, normal body fat percentage, and no soy allergy.
✕Probably not a fit
Participants with pregnancy, lactation, recent medical issues, antibiotic use, smoking, soy allergy, or unusually high protein intake may not benefit from the study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Healthy, reproductive-age women will participate in a crossover design across seven 3-day trial periods to compare methionine from tempeh chips with a crystalline amino acid mix. The study uses the indicator amino acid oxidation method to measure methionine utilization after controlled diets and a 12-hour fast. Participants receive energy- and protein-matched meals, with washout periods between dietary phases, and undergo baseline measurements like weight, height, and resting energy expenditure. The protocol is conducted at Universiti Kebangsaan Malaysia, with the National University of Malaysia as lead sponsor and IAEA as a collaborator.
Why it matters
Potential benefit: Results could clarify tempeh’s protein quality and methionine availability, potentially expanding vegetarian protein options for women.
How similar studies have gone: Prior research using stable isotope methods has demonstrated the feasibility of measuring amino acid availability in foods like soy products; this approach is established but the tempeh-specific data are novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Universiti Kebangsaan Malaysia Kuala Lumpur campus female students and staffs aged 19 - 30 years old * Malaysian * Have consistent weight in the past 6 months * Have a normal body fat percentage (20% - 29.9%) Exclusion Criteria: * Pregnant women * Lactating women * Reported serious medical or surgical ailments 3 months prior to start of the study * On dietary or nutrient supplements or who had taken antibiotics 4 weeks before the initiation of the study * Smoking * Allergy to soybean * Excessively high protein intake in the past 6 months
Where it's running
-
Universiti Kebangsaan Malaysia Kampus Kuala Lumpur
Kuala Lumpur, Malaysia Recruiting
Study contacts
- Study coordinator: Hasnah Haron Associate Professor Ts. Dr.
- Email: hasnaharon@ukm.edu.my
- Phone: +60133996594
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.