Metacognitive therapy for obsessive-compulsive disorder

The Efficacy of Metacognitive Therapy for Obsessive-compulsive Disorder

Not applicable Interventional Northeast Normal University · NCT06466057

This study is testing if metacognitive therapy can help reduce obsessive-compulsive symptoms in people from China compared to a treatment that doesn't include therapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages12 Years to 60 Years
SexAll
SponsorNortheast Normal University Academic / other
Locations1 site (Changchun, Jilin)
Trial IDNCT06466057 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of metacognitive therapy in reducing obsessive-compulsive symptoms among a Chinese population. Participants will be randomly assigned to either receive metacognitive therapy or a control treatment without psychotherapy for a duration of 8 to 15 weeks. The study will assess changes in obsessive-compulsive symptoms and metacognitive beliefs using standardized measures before, after, and 12 weeks post-intervention. The goal is to determine if metacognitive therapy can significantly improve outcomes for individuals with obsessive-compulsive disorder.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with obsessive-compulsive disorder who have a junior high school education or higher and are willing to participate voluntarily.

Not a fit: Patients with severe psychotic symptoms, significant depression, or a history of substance abuse may not benefit from this therapy.

Why it matters

Potential benefit: If successful, this therapy could provide a new effective treatment option for patients suffering from obsessive-compulsive disorder.

How similar studies have performed: While metacognitive therapy is a relatively novel approach for OCD, similar studies have shown promising results in other populations, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* two psychiatrists with the title of Deputy Chief Physician or above jointly determine that the above diagnostic criteria were met
* education level of junior high school or above, without mental retardation or audio-visual disorders
* participation in the study is voluntary, and the informed consent is signed by the patient or his/her guardian

Exclusion Criteria:

* loss of or insufficient self-awareness, the presence of hallucinations, delusions, and other psychotic symptoms
* the presence of severe depression, or self-inflicted suicidal attempts and behaviors
* the presence of a history of alcohol or drug abuse
* refusal of psychotherapy, or the ineffectiveness of those who had been involved in a full course of psychotherapy.

Where this trial is running

Changchun, Jilin

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Obsessive-Compulsive DisorderMetacognitive Therapy
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.