Clinical trial Recruiting at 1 site Observational Ages 18 and up Men only

Men's experiences with ICSI and low sperm quality

Official title: Male Experiences With Intra Cytoplasmic Sperm Injection (ICSI) and Reduced Sperm Quality - Have Anything Changed the Past 15 Years?

Run by Regionshospitalet Viborg, Skive · NCT07546435 · Data updated 2026-11-12

This project will see if Danish men with low sperm quality who undergo ICSI have lower quality of life or low testosterone and how they experience interactions with health professionals.

Quick facts

Study typeObservational
Ages18 Years and up
SexMen only
Enrollment400 (estimated)
SponsorRegionshospitalet Viborg, Skive
Academic / other
Locations1 site (Skive, Midt Jylland)
StatusRecruiting
StartedFebruary 13, 2026
Main results expectedJanuary 15, 2029
Study endsJanuary 15, 2029
Registry record updatedApril 22, 2026
Trial IDNCT07546435 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are Danish-speaking men undergoing ICSI due to reduced semen quality who are not sterilized and do not have a history of cancer or PESA/TESA procedures.

Probably not a fit

Men who have had PESA/TESA, who are sterilized, who have cancer, or who do not speak Danish are excluded and unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project enrolls Danish-speaking men receiving ICSI because of reduced semen quality at Regionshospitalet Skive. Participants will complete questionnaires about psychological experience, social interaction, and quality of life, and their testosterone status will be recorded to identify possible hypogonadism. The study aims to update Danish data and compare current patient needs and healthcare interactions with findings from the past 15 years. No experimental treatments are given; the work focuses on patient-reported outcomes and hormone measurements.

Why it matters

Potential benefit: If successful, the findings could improve recognition of men's needs during fertility care and lead to better counseling and consideration of testosterone screening.

How similar studies have gone: International qualitative and survey research has consistently shown men with reduced semen quality experience stigma and negative emotions, but updated Danish data and clear links between testosterone levels and quality of life are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ICSI treatment caused by reduced semen quality, language (danish)

Exclusion Criteria:

* PESA/TESA, Cancer, Sterilized males

Where it's running

  • Regionshospitalet
    Skive, Midt Jylland, Denmark
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.