Memory training program for people with early memory problems
Official title: CogMed Intervention Targeting Working Memory in Patients with Mild Cognitive Impairment
Run by St. Joseph's Hospital and Medical Center, Phoenix · NCT06734286 · Data updated 2026-11-12
This study is testing if a memory training program can help people with early memory problems feel better and improve their memory while also looking at a blood marker related to Alzheimer's disease.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 50 Years and up |
| Sex | All |
| Enrollment | 10 (estimated) |
| Sponsor | St. Joseph's Hospital and Medical Center, Phoenix Academic / other |
| Locations | 1 site (Phoenix, Arizona) |
| Status | Recruiting |
| Started | September 16, 2024 |
| Main results expected | June 30, 2025 |
| Study ends | September 30, 2025 |
| Registry record updated | December 16, 2024 |
| Trial ID | NCT06734286 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are outpatients aged 50 and older who meet the Mayo Clinic criteria for Mild Cognitive Impairment.
✕Probably not a fit
Patients with moderate or severe dementia or those with significant cognitive impairment as indicated by a low Mini Mental State Exam score may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to evaluate the effectiveness of a memory training program called CogMed in patients with Mild Cognitive Impairment (MCI). Participants will be divided into two groups: one receiving the CogMed intervention alongside standard treatment and the other receiving standard treatment alone. The study will also assess changes in a blood biomarker, p-Tau 217, which may indicate the presence of Alzheimer's disease. The goal is to determine if the CogMed training can enhance memory function and reduce perceived stress in participants. Additionally, the feasibility of collecting blood samples for biomarker analysis will be explored.
Why it matters
Potential benefit: If successful, this program could improve memory function and reduce stress in patients with Mild Cognitive Impairment.
How similar studies have gone: Previous studies have shown promise in cognitive training interventions for MCI, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Male or female outpatients ages ≥ 50 years; 2. Meet Mayo Clinic Criteria for MCI. (Patients with mild cognitive impairment) 3. Access to the internet through computer 4. A proficiency in speaking and reading English or having a family member who is proficient in reading and speaking English and is willing to serve as a translator. 5. Vision and hearing must be sufficient to comply with study procedures. Exclusion Criteria: 1. Mini Mental State Exam (MMSE) score less than 19 or patients diagnosed with moderate or severe dementia by a clinician. 2. In the opinion of the investigator, participation would not be in the best interest of the subject.
Where it's running
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Barrow Neurological Institute, Division of Alzheimer's Disease
Phoenix, Arizona, United States Recruiting
Study contacts
- Principal investigator: Yonas E Geda, M.D, MSc — Barrow Neurological Institute, Alzheimer's Disease and Cognitive Disorders Division
- Study coordinator: Yonas E Geda, M.D, MSc
- Email: yonas.geda@commonspirit.org
- Phone: 833-233-3073
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.