Melatonin lotion's effects on sleep and mental health

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines how melatonin lotion affects sleep quality and mental health in young adults experiencing sleep problems, depression, and anxiety. Participants will use melatonin lotion and a placebo lotion in a randomized crossover design, applying the lotion before bedtime for one week each. Throughout the study, they will wear devices to monitor sleep and heart rate, complete mood assessments, and provide saliva samples. The goal is to determine the effectiveness of melatonin lotion in improving sleep and mental health outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* a T score ≥ 48 on the sleep disturbance short form Patient-Reported Outcomes Measurement Information System (PROMIS) measure, and
* a T score ≥ 55 on the anxiety or depression short form PROMIS measures (mild symptoms or more)

Exclusion Criteria:

* currently using antidepressant, anti-anxiety, or sleep medication including melatonin
* are pregnant
* have allergies/sensitivities to scented lotion
* are unwilling to commit to keeping a similar bedtime (± 1 hour) during treatment weeks.

Where it's running

• University of Redlands
  Redlands, California, United States Recruiting

Study contacts

• Principal investigator: Lisa E Olson, Ph.D. — University of Redlands
• Study coordinator: Lisa E Olson, Ph.D.
• Email: lisa_olson@redlands.edu
• Phone: 909-748-8524

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• AI chatbot for improving sleep in adults

  A chatbot-based AI sleep program is being tested to see if it helps adults with sleep problems sleep better.

  Recruiting New York University · New York, New York and 1 other locations · NCT07718750

• Sleep problems before heart surgery may affect recovery outcomes

  This study tests whether preoperative sleep issues in adults undergoing cardiac surgery are linked to different perioperative metabolites and postoperative outcomes.

  Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing, Beijing Municipality · NCT07588178

• Digital sleep treatment for teens with insomnia after hospitalization

  This project will try a six-session digital cognitive behavioral therapy for insomnia (Sleepio) plus usual care to see if it helps 14–18-year-olds recently hospitalized for suicide risk who have insomnia.

  Recruiting at 2 sites Rutgers, The State University of New Jersey · Piscataway, New Jersey and 1 other locations · NCT07303959

• Special blankets to improve sleep for 16–24-year-olds

  This project will test whether special tactile or weighted blankets help 16–24‑year‑olds with insomnia sleep better.

  Recruiting Aarhus University Hospital · Aarhus · NCT07181577

• Pre-surgery sleep program to reduce delirium after congenital heart surgery in infants and toddlers

  This study will try a short cognitive-behavioral sleep program before elective congenital heart surgery to see if it lowers postoperative delirium in infants and toddlers (0–36 months) with sleep problems.

  Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing · NCT06879431

• Improving sleep before heart surgery to reduce delirium in young children

  This study is testing if a special bedtime routine can help young children sleep better before heart surgery and reduce the chances of them experiencing confusion afterward.

  Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing · NCT06861998

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.