Mediterranean versus Paleolithic diet for adults with rheumatoid arthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with rheumatoid arthritis will be randomly assigned to follow a Mediterranean diet, a Paleolithic diet, or continue their usual diet for 12 weeks at Kasr Al-Ainy Hospital in Cairo. The trial will collect anthropometric measurements, disease activity scores (DAS28), laboratory markers (CBC, CRP, ESR, lipid profile, fasting glucose, HbA1c), and patient-reported outcomes including fatigue, sleep, and quality of life. Dietary intake will be monitored using questionnaires and nutritional assessments at baseline and after the intervention. The goal is to determine whether specific dietary patterns reduce inflammation, improve sarcopenia-related measures, and enhance overall well-being in this patient group.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients classified as having rheumatoid arthritis according to the 2010 rheumatoid arthritis ACR/ EULAR classification criteria with a selected age group of 40 to 60 years old.

Exclusion Criteria:

* Patients with comorbidities (e.g., diabetes mellitus, hypertension, gout, thyroid dysfunction).

Where it's running

• Kasr Al Ainy Hospital, Faculty of Medicine, Cairo University
  Cairo, Al-Manial, Egypt Recruiting

Study contacts

• Study coordinator: Gehad Maghraby, MD
• Email: gehad.maghraby@kasralainy.edu.eg
• Phone: +201027491363

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.