Measuring tongue muscle function in children with obstructive sleep apnea
Official title: Tongue Muscular Assessment in Children Referred for Polysomnography in a Context of Suspected Obstructive Sleep Apnea
Run by Hospices Civils de Lyon · NCT07273019 · Data updated 2026-11-12
This project tests tongue strength and movement in children with suspected obstructive sleep apnea to see if tongue function contributes to breathing problems during sleep.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 4 Years to 17 Years |
| Sex | All |
| Enrollment | 78 (estimated) |
| Sponsor | Hospices Civils de Lyon Academic / other |
| Locations | 1 site (Bron) |
| Status | Recruiting |
| Started | March 26, 2026 |
| Main results expected | March 26, 2028 |
| Study ends | March 26, 2028 |
| Registry record updated | July 30, 2026 |
| Trial ID | NCT07273019 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children referred for polysomnography with suspected sleep-disordered breathing who have informed consent from both legal guardians, understand French, and are affiliated to a social security scheme.
✕Probably not a fit
Children with major neurological, cardiac, or respiratory disorders, prior upper-airway or oral surgery, craniofacial malformations, intellectual deficits preventing cooperation, or insufficient French comprehension are excluded and unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study measures tongue motor function in children referred for polysomnography for suspected sleep-disordered breathing and compares results with healthy children from a concurrent TMAC dataset. Participants undergo overnight polysomnography, quantitative tongue strength and motor testing, standardized questionnaires about sleep and daytime functioning, and anthropometric measurements. Investigators will compare motor function metrics between children with OSA and healthy controls to identify myofunctional deficits linked to persistent obstruction. The goal is to clarify the tongue's role in pediatric OSA and inform targeted therapeutic approaches.
Why it matters
Potential benefit: If successful, the findings could help identify tongue-related causes of persistent OSA in children and guide targeted treatments such as myofunctional therapy or tailored surgical planning.
How similar studies have gone: Previous work indicates the tongue can be a site of airway obstruction and some myofunctional therapy studies show benefit, but direct pediatric tongue motor testing is limited and relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * With suspected sleep-disordered breathing * Referred for polysomnography * Affiliated to a social security scheme * With informed consent from both legal representatives Exclusion Criteria: * Insufficient comprehension of French language * Regarding patients with suspected OSA type I or II: * Neurological, cardiac, or unstable respiratory conditions other than sleep disorders and their repercussions * Any deficit possibly impacting measurements according to the investigator (e.g., psychiatric condition) * Malformation of the skull, the upper airway or the oral cavity * Regarding patients with suspected OSA type III: * Any deficit possibly impacting measurements according to the investigator (e.g., psychiatric condition) * Intellectual deficit impeding the understanding of instructions
Where it's running
-
Hôpital Femme-Mère-Enfant : Service d'épileptologie clinique, des troubles du sommeil et de neurologie fonctionnelle de l'enfant
Bron, France Recruiting
Study contacts
- Study coordinator: Patricia FRANCO, MD, PhD
- Email: patricia.franco@chu-lyon.fr
- Phone: +33 4 27 85 60 52
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.