Measuring oxygen levels during intense squat exercises

Analysis of Local and Systemic Oxygen Saturation During Monotonous Exercise Using the Example of 'Death by Squats'

Bundeswehr University Munich · NCT06884644

This study is testing how intense squat exercises affect oxygen levels and fatigue in active individuals to see how hard they can push themselves.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorBundeswehr University Munich (other)
Locations1 site (Munich, Bavaria)
Trial IDNCT06884644 on ClinicalTrials.gov

What this trial studies

This observational study investigates the effects of a high-intensity squat exercise protocol, termed 'Death by Squats', on oxygen saturation and fatigue levels in participants. A group of 25-30 moderately to severely physically active individuals will perform bodyweight squats until maximum exertion, while their heart rate and muscle oxygen saturation are monitored. Blood lactate levels will be measured at rest and peak exertion, and participants will report their perceived exertion and reasons for stopping the exercise. The study aims to gather data from April 2023 to December 2024.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals who are moderately to severely physically active, engaging in at least 2 hours of exercise per week.

Not a fit: Patients with acute infections, musculoskeletal injuries, or chronic cardiovascular or pulmonary diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of muscle oxygenation and fatigue during high-intensity exercise, potentially informing training and rehabilitation protocols.

How similar studies have performed: While similar studies on exercise physiology exist, this specific approach to measuring local and systemic oxygen saturation during a unique squat protocol is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* being moderately to severely physically active al least 2 hours/week (all types of sport are eligible)

Exclusion Criteria:

* akute infections, musculoskeletal injuries
* chronic cardiovascular or pulmonary diseases (in case of uncertainty, we recommend appraisal from medical personnel)

Where this trial is running

Munich, Bavaria

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Oxygen Saturation, Fatigue, Anaerobic Threshold, Quadriceps Muscle

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.