Measuring optic nerve sheath diameter to assess neurological deficits in stroke patients

Correlation Between Optic Nerve Sheath Diameter Measured by POCUS and Neurological Deficit in Physical Examination in Adult Patients with Suspected Ischemic Stroke Evaluated in Emergency Departments

Observational Clinica Mexico · NCT06492681

This study tests if measuring the optic nerve sheath diameter with ultrasound can help doctors understand neurological problems in adults who might be having a stroke.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorClinica Mexico Academic / other
Locations1 site (Piedras Negras, Coahuila)
Trial IDNCT06492681 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the correlation between the ultrasound measurement of the optic nerve sheath diameter and the side of neurological focus in adult patients presenting with suspected ischemic stroke in emergency departments. The study will involve adult patients who meet specific inclusion criteria, and will utilize high-frequency ultrasound to measure the optic nerve sheath diameter. Data collected will include demographic, clinical, and ultrasound information to analyze the relationship between the measurements and neurological deficits.

Who should consider this trial

Good fit: Ideal candidates are adult patients (≥18 years) presenting to the emergency department with suspected acute ischemic stroke.

Not a fit: Patients with contraindications for ocular ultrasound or a history of previous ocular surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the diagnostic accuracy for identifying the side of neurological focus in patients with suspected ischemic stroke.

How similar studies have performed: While the use of optic nerve sheath diameter measurement in stroke assessment is gaining interest, this specific correlation has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with suspected acute ischemic stroke
* CT scan negative to hemorrhagic stroke
* Informed consent

Exclusion Criteria:

* Contraindications to perform ocular ultrasound
* Patients with ocular surgery

Where this trial is running

Piedras Negras, Coahuila

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ischemic Strokeoptic nerve sheath diameterstrokeemergency department
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.