Measuring nerve responses during facial pain treatment
Trigeminal Evoked Responses to Improve Rhizotomy
University of Minnesota · NCT05269472
This study is testing how nerve responses change in people with trigeminal neuralgia before and after a specific pain treatment to better understand the effects of the procedure.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Minnesota (other) |
| Locations | 1 site (Minneapolis, Minnesota) |
| Trial ID | NCT05269472 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess somatosensory evoked responses in patients undergoing percutaneous rhizotomy for trigeminal neuralgia. The study will measure these responses at two locations: the contralateral scalp using EEG and at the gasserian ganglion with an FDA-approved electrode. By analyzing these responses before and after the rhizotomy procedure, the study seeks to enhance understanding of the electrophysiological changes associated with trigeminal neuralgia treatment.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older scheduled for percutaneous rhizotomy due to facial pain from trigeminal neuralgia.
Not a fit: Patients with facial pain of unclear origin or those whose rhizotomy procedure has been canceled may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the understanding of trigeminal neuralgia treatment and potentially lead to better management strategies for patients.
How similar studies have performed: While this approach is observational and may build on existing knowledge, similar studies have not been widely reported, indicating a novel exploration in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria (TGN): * Adults of 18 years or older * Scheduled to undergo percutaneous rhizotomy for facial pain Exclusion Criteria (TGN): * Facial pain of unclear origin (i.e. not clearly TGN pain) * Rhizotomy procedure canceled Inclusion Criteria (Healthy controls) * Adults of 18 years or older Exclusion Criteria (Healthy Controls) * Diagnosis or history of facial pain such as TMD or TGN * History of migraine * History of any functional pain disorder: fibromyalgia, IBS, CRPS * Recent chronic pain (within last month) * Unwilling to participate for two hours in lab * Current acute pain
Where this trial is running
Minneapolis, Minnesota
- University of Minnesota — Minneapolis, Minnesota, United States (RECRUITING)
Study contacts
- Principal investigator: David Darrow — University of Minnesota
- Study coordinator: Matthew Maple
- Email: maple036@umn.edu
- Phone: 612-946-1424
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Trigeminal Neuralgia