Measuring daily activity in patients with ALS and healthy controls

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to continuously measure the activity levels of patients diagnosed with amyotrophic lateral sclerosis (ALS) and compare them with healthy control subjects. Approximately 20 ALS patients will be enrolled voluntarily and assessed every three months over a year. Participants will undergo various clinical examinations and tests, including the 6-minute walk test and electromyography, and will wear a device called Actimyo daily for one month to monitor their activity levels. The study seeks to gather comprehensive data on the daily living activities of ALS patients to better understand the disease's impact.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinically defined or probable diagnosis of ALS according to El Escorial criteria revised with Awaji's electro-diagnostic algorithm.
* Over 18 years old.
* Signed informed consent
* If patient on Riluzole, the dosage should be stable for 1 month and continued throughout the study period.

Exclusion Criteria:

* Patients with excessive cognitive disorders, limiting the understanding of task or with apparent communication difficulties hindering data collection.
* Any other previous or present pathology having an impact on motor function.
* Recent surgery or trauma (less than 6 months) in the upper or lower limbs.
* Prior neurological, endocrine, infectious, allergic, or chronic or acute inflammatory pathology in the three weeks preceding inclusion.
* Patients participating in an interventional clinical trial.

Where it's running

• CHR Citadelle
  Liège, Liège, Belgium Recruiting

Study contacts

• Principal investigator: Margaux Poleur, MD — CHR Citadelle-CHU liège
• Study coordinator: Laurie MEDARD
• Email: Laurie.Medard@citadelle.be
• Phone: 43218222

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.