Maximizing lymph node removal from lung surgery specimens

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Patients with early-stage non-small cell lung cancer scheduled for upfront lobectomy will have their resected lung specimens processed using a standardized dissection technique on fresh and fixed tissue. Pathologists will compare the number and stations of lymph nodes retrieved using the standardized method versus usual specimen processing. The study will track changes in pathological stage, especially identification of N1 stations, and the potential impact on adjuvant therapy recommendations. Outcomes include lymph node yield, nodal staging shifts, and feasibility of adopting the technique in routine pathology workflow.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Subjects with a lung nodule or mass who are eligible to undergo a lobectomy.
2. Subject without any metastasis present.
3. Subjects who have peripheral lung nodule location
4. Subjects must be 18 years of age or older.

Exclusion Criteria:

1. Subjects who received preoperative chemotherapy or radiotherapy.
2. Subjects who have a lung nodule located in a central location. Central tumors are defined by those infiltrating the lobar airway.

Where it's running

• Brigham and Womens Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Study coordinator: Paula Ugalde Figueroa, M.D.
• Email: pugaldefigueroa@bwh.harvard.edu
• Phone: (617) 732-7696

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.