Mapping electrical properties in the brain
Mapping of Electrical Properties in the Brain.
Mayo Clinic · NCT06470711
This study is testing new MRI methods to see if they can help doctors better understand and diagnose brain tumors by looking at the brain's electrical activity.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic (other) |
| Locations | 1 site (Scottsdale, Arizona) |
| Trial ID | NCT06470711 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates imaging methods to monitor neural and electrical activity in the brain, aiming to enhance clinical diagnosis of malignant glioma. The study focuses on optimizing MRI pulse sequences and developing models that depict the brain's electrical properties, such as resistivity and current. It also seeks to correlate these MRI models with existing imaging techniques and clinical features to improve understanding of neural integrity and function. Participants will complete a survey and undergo MRI scans as part of the study.
Who should consider this trial
Good fit: Ideal candidates include healthy volunteers and patients who have undergone surgical biopsy or resection for suspected or known glioma.
Not a fit: Patients who are healthy volunteers but unable to undergo MRI will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic methods for malignant glioma, enhancing patient outcomes.
How similar studies have performed: Other studies have shown promise in using advanced MRI techniques for brain imaging, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aim 1: normal healthy volunteers * Aim 2, 3, 4: participants included in IRB 16-002424, including those that have undergone surgical biopsy/resection for suspected or known glioma Exclusion Criteria: * Healthy volunteer unable to have an MRI
Where this trial is running
Scottsdale, Arizona
- Mayo Clinic in Arizona — Scottsdale, Arizona, United States (RECRUITING)
Study contacts
- Principal investigator: Leland S. Hu, MD — Mayo Clinic
- Study coordinator: Clinical Trials Referral Office
- Email: mayocliniccancerstudies@mayo.edu
- Phone: 855-776-0015
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Malignant Glioma