Manual therapy for tension-type headache in premenopausal and menopausal women
Comparison of the Effect of Manuel Therapy on Tension Type Headache in Menopausal and Premenopasual Women
We will test whether manual therapy can reduce pain and improve function in premenopausal and menopausal women with tension-type headache.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 45 Years to 65 Years |
| Sex | Female |
| Sponsor | Necmettin Erbakan University Academic / other |
| Locations | 1 site (Konya, Konya) |
| Trial ID | NCT07477483 on ClinicalTrials.gov |
What this trial studies
Researchers will apply manual therapy (soft tissue techniques, cervical mobilization, and therapeutic exercises) to women aged 45–65 diagnosed with tension-type headache and compare responses between premenopausal and menopausal participants. Outcomes measured before and after the intervention include headache intensity (VAS), headache-related disability (HIT-6), pressure pain threshold (algometer), cervical range of motion (goniometer), sleep quality (PSQI), and health-related quality of life (SF-36). Participants must meet inclusion criteria such as HIT-6 ≥ 49 and must not be using hormonal therapy or have a history of cervical surgery or neurological disease. All treatments and assessments are delivered in person at Necmettin Erbakan University in Konya, Turkey.
Who should consider this trial
Good fit: Ideal candidates are women aged 45–65 with a clinical diagnosis of tension-type headache, HIT-6 score ≥ 49, premenopausal or menopausal status, able to attend in-person sessions, and not using hormonal therapy or having prior cervical surgery or neurological disease.
Not a fit: Patients who are male, have other primary headache types (for example migraine), are on hormonal therapy, have a history of cervical surgery or neurological disease, are pregnant, or cannot attend treatment sessions are unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, the approach could lower headache pain and related disability and improve sleep and quality of life for women with tension-type headache.
How similar studies have performed: Previous trials of manual therapy and neck-targeted exercises have shown modest reductions in tension-type headache pain and frequency, but direct comparisons by menopausal status are largely novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Women aged between 45 and 65 years Diagnosed with tension-type headache Premenopausal or menopausal status HIT-6 score ≥ 49 Willing to participate in the study Exclusion Criteria: Use of hormonal therapy History of cervical surgery History of neurological disease Pregnancy Inability to understand questionnaires Failure to attend treatment sessions
Where this trial is running
Konya, Konya
- Necmettin Erbakan Univesity Faculty of Health Sciences — Konya, Konya, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Neslihan Altuntaş Yılmaz, PhD — Necmettin Erbakan University
- Study coordinator: Ayça Seda Yıldırımer, PT, MSc
- Email: aycaseda29@gmail.com
- Phone: +90 507 409 08 99
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.