Managing heavy menstrual bleeding in adolescents with hormonal treatments
Hormonal Management of Heavy Menstrual Bleeding in Adolescents and Young Adults With and Without a Bleeding Disorder: a Prospective Observational Cohort Study
This study is testing how well hormonal treatments can help teenagers with heavy menstrual bleeding, whether or not they have bleeding disorders.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 163 (estimated) |
| Ages | N/A to 25 Years |
| Sex | Female |
| Sponsor | University Hospital, Geneva Academic / other |
| Locations | 1 site (Geneva) |
| Trial ID | NCT06740929 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the effectiveness of hormonal medications, such as contraceptive pills, patches, injectable progestins, and hormonal intra-uterine devices, in managing heavy menstrual bleeding among adolescents with and without bleeding disorders. Participants will undergo assessments including questionnaires and blood tests to monitor hemoglobin and iron levels, as well as quality of life. The study will follow participants for one year to compare outcomes between those with bleeding disorders and those without.
Who should consider this trial
Good fit: Ideal candidates are adolescents and young adults under 26 years old diagnosed with heavy menstrual bleeding who are willing to start hormonal treatment.
Not a fit: Patients who are pregnant, planning to become pregnant, or currently using hormonal medications for menstrual management may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide effective hormonal management options for adolescents suffering from heavy menstrual bleeding, improving their quality of life.
How similar studies have performed: While similar studies have explored hormonal management for heavy menstrual bleeding, this specific comparison between adolescents with and without bleeding disorders is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adolescents and young adults aged \< 26yo * Presenting to the gynecology consultation at HUG * Diagnosed with heavy menstrual bleeding (PBAC \> 100) * Willing to initiate a hormonal medication to manage heavy menstrual bleeding Exclusion Criteria: * Pregnancy or planning to become pregnant during the study period * Already using hormonal medication for menstrual management and/or contraception * Known anatomical uterine pathology * Using anticoagulant or antiaggregant agents
Where this trial is running
Geneva
- Geneva University Hospitals — Geneva, Switzerland (Recruiting)
Study contacts
- Study coordinator: Dehlia Moussaoui, MD
- Email: dehlia.moussaoui@hug.ch
- Phone: +41 22 372 33 87
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.