Managing fluid strategies to reduce blood loss during liver transplantation
Official title: Effects of Different Fluid Management Strategies on Blood Loss, Inflammatory Response, and Major Organ Sequelae in Liver Transplantation
Run by National Taiwan University Hospital · NCT06215404 · Data updated 2026-11-12
This study tests whether using different fluid management strategies during liver transplantation can help reduce blood loss and improve outcomes for patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Status | Recruiting |
| Started | January 15, 2024 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | April 11, 2025 |
| Trial ID | NCT06215404 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults aged 18 to 75 with end-stage liver disease who are expected to receive a liver transplant.
✕Probably not a fit
Patients with arrhythmias may not benefit from this study due to exclusion criteria.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of different fluid management strategies on blood loss during liver transplantation. It employs a randomized group model to compare restrictive and liberal infusion approaches, utilizing the PiCCO monitor to assess cardiac output and stroke volume variation. The goal is to determine how these strategies impact bleeding volume and potential complications in major organs during the surgery.
Why it matters
Potential benefit: If successful, this study could lead to improved outcomes and reduced complications for patients undergoing liver transplantation.
How similar studies have gone: Previous studies have shown that restrictive fluid management can effectively reduce bleeding in liver transplantation, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * end stage liver disease * age between 18y/o to 75 y/o * expected to recieve to receive liver transplantation Exclusion Criteria: * arrythmia
Where it's running
-
National Taiwan University Hospital
Taipei, Taiwan Recruiting
Study contacts
- Principal investigator: Kuang-Cheng Chan, M.D.,PhD. — Department of Anesthesiology, National Taiwan University Hospital
- Study coordinator: Kuang-Cheng Chan, M.D.,PhD.
- Email: jkjchan@gmail.com
- Phone: +886-2-23123456
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.