Clinical trial Recruiting at 1 site Interventional Ages 18 to 75

Managing fluid strategies to reduce blood loss during liver transplantation

Official title: Effects of Different Fluid Management Strategies on Blood Loss, Inflammatory Response, and Major Organ Sequelae in Liver Transplantation

Run by National Taiwan University Hospital · NCT06215404 · Data updated 2026-11-12

This study tests whether using different fluid management strategies during liver transplantation can help reduce blood loss and improve outcomes for patients.

More Liver Transplant trials

Quick facts

Study typeInterventional
Ages18 Years to 75 Years
SexAll
Enrollment60 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Locations1 site (Taipei)
StatusRecruiting
StartedJanuary 15, 2024
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedApril 11, 2025
Trial IDNCT06215404 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adults aged 18 to 75 with end-stage liver disease who are expected to receive a liver transplant.

Probably not a fit

Patients with arrhythmias may not benefit from this study due to exclusion criteria.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of different fluid management strategies on blood loss during liver transplantation. It employs a randomized group model to compare restrictive and liberal infusion approaches, utilizing the PiCCO monitor to assess cardiac output and stroke volume variation. The goal is to determine how these strategies impact bleeding volume and potential complications in major organs during the surgery.

Why it matters

Potential benefit: If successful, this study could lead to improved outcomes and reduced complications for patients undergoing liver transplantation.

How similar studies have gone: Previous studies have shown that restrictive fluid management can effectively reduce bleeding in liver transplantation, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* end stage liver disease
* age between 18y/o to 75 y/o
* expected to recieve to receive liver transplantation

Exclusion Criteria:

* arrythmia

Where it's running

  • National Taiwan University Hospital
    Taipei, Taiwan
    Recruiting

Study contacts

  • Principal investigator: Kuang-Cheng Chan, M.D.,PhD. — Department of Anesthesiology, National Taiwan University Hospital
  • Study coordinator: Kuang-Cheng Chan, M.D.,PhD.
  • Email: jkjchan@gmail.com
  • Phone: +886-2-23123456

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.