Managing congestion in heart failure with a remote monitoring device
Managing Congestion in Heart Failure: Pressure- and Volume- Based. A Mechanistic Study in Patients With HFpEF (MAGIC-HF)
This study is testing whether a remote monitoring device can help people with heart failure keep track of their fluid levels and improve their treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Otto-von-Guericke University Magdeburg Academic / other |
| Locations | 1 site (Magdeburg, Saxony-Anhalt) |
| Trial ID | NCT06977477 on ClinicalTrials.gov |
What this trial studies
The MAGIC-HF clinical trial aims to improve the management of congestion in patients with heart failure with preserved ejection fraction (HFpEF) through daily remote monitoring. Participants will use the CardioMEMS™ device to measure pulmonary artery pressure and a smart scale to assess body water levels. This prospective, multi-center study will collect data over six months to evaluate the relationship between pressure and volume in managing fluid buildup. The goal is to enhance early detection of decompensation and optimize treatment strategies.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with HFpEF who have been hospitalized for acute decompensated heart failure and require intravenous diuretics.
Not a fit: Patients with cardiogenic shock, recent acute myocardial infarction, or those with chronic kidney disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to better management of heart failure symptoms and reduced hospitalization rates for patients.
How similar studies have performed: While the approach of combining pressure and volume monitoring is innovative, similar studies have shown promise in improving heart failure management.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years of age or older * Patients with HFpEF, who are hospitalized for acute decompensated heart failure and require treatment with intravenous (IV) diuretics. * Signed informed consent. Exclusion Criteria: * Patients admitted with cardiogenic shock and/or those who required inotropic or vasopressor support. * Had a history of cardiac transplantation or ventricular assist device (VAD) implantation. * Had any implanted cardiac device (pacemaker, ICD, CRT-D. * Had chronic kidney disease with creatinine clearance \< 20 ml/min. * Had recent acute MI or CABG within 3 months.
Where this trial is running
Magdeburg, Saxony-Anhalt
- Otto von Guericke University, Faculty of Medicine — Magdeburg, Saxony-Anhalt, Germany (Recruiting)
Study contacts
- Study coordinator: Tarek Bekfani, MD, MSc
- Email: tarek.bekfani@med.ovgu.de
- Phone: +49-391-67-14469
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.