Managing bleeding during liver transplantation
Official title: Perioperative Hemostasis Management in Liver Transplantation
Run by Société Française d'Anesthésie et de Réanimation · NCT06257407 · Data updated 2026-11-12
This study looks at how to better manage bleeding during liver transplants by understanding what causes it and how much blood patients might need during the surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1200 (estimated) |
| Sponsor | Société Française d'Anesthésie et de Réanimation Academic / other |
| Locations | 16 sites (Besançon and 15 other locations) |
| Status | Recruiting |
| Started | October 17, 2024 |
| Main results expected | October 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 2, 2026 |
| Trial ID | NCT06257407 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and over who are undergoing liver transplantation.
✕Probably not a fit
Patients undergoing multi-organ transplantation or those not affiliated with a social security scheme may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on the management of hemostasis during liver transplantation, a procedure associated with significant bleeding risks. It aims to identify and analyze various risk factors that contribute to intraoperative bleeding and transfusion needs, which can occur at different phases of the surgery. By examining patient characteristics and surgical phases, the study seeks to improve predictive models for transfusion requirements, ultimately enhancing patient outcomes during liver transplantation.
Why it matters
Potential benefit: If successful, this study could lead to better management strategies for bleeding during liver transplantation, reducing the need for transfusions and improving surgical outcomes.
How similar studies have gone: While there have been studies on hemostasis in liver transplantation, this approach focuses specifically on the intraoperative phases and may provide novel insights into transfusion management.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 or over * Liver transplant patient Exclusion Criteria: * Multi-organ transplantation * Protected populations: under guardianship or curatorship * Patients not affiliated to a social security scheme
Where it's running
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Chru Minjoz
Besançon, France Recruiting -
CHU Claude Huriez
Lille, France Recruiting -
Hôpital de la Croix-Rousse
Lyon, France Recruiting -
Hôpital Paul Brousse
Villejuif, France Recruiting -
CHU Estaing
Clermont, France Not yet recruiting -
Hôpital Beaujon
Clichy, France Not yet recruiting
Show 10 more locations
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CHU Grenoble Alpes
Grenoble, France Not yet recruiting -
CHU La Timone
Marseille, France Not yet recruiting -
Hôpital St Eloi
Montpellier, France Not yet recruiting -
Hôpital De L'Archet 2
Nice, France Not yet recruiting -
CHU Pitié-Salpêtrière
Paris, France Not yet recruiting -
CHU Haut Levêque
Pessac, France Not yet recruiting -
CHU Pontchaillou
Rennes, France Not yet recruiting -
CHU Hautepierre
Strasbourg, France Not yet recruiting -
CHU Toulouse Rangueil
Toulouse, France Not yet recruiting -
CHU Tours
Tours, France Not yet recruiting
Study contacts
- Principal investigator: Weiss, Md — Hôpital Beaujon
- Study coordinator: Emmanuel WEISS, MD
- Email: emmanuel.weiss@aphp.fr
- Phone: +33 1 40 87 58 81
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Expanding HIV-positive donor livers for HIV-positive recipients
This study tests whether liver transplants from HIV-positive donors to HIV-positive recipients are safe regarding opportunistic infections and cancer.
-
Magnetic Resonance Cholangiopancreatography to help living liver donors and their recipients
This study tests whether preoperative MRCP imaging can help select living liver donors and reduce biliary complications in recipients.
-
Reducing Immunosuppression by 50% in Young Liver Transplant Recipients
This study tests whether cutting the immunosuppressive medicine by half in children with liver transplants is safe and effective.
-
Preoperative Carbohydrate Loading Before Liver Transplant
This study tests whether drinking a carbohydrate beverage before anesthesia helps liver transplant patients recover faster.
-
Doctor counseling plus smartphone apps to support healthy eating and activity after liver or kidney transplant
This program tries whether doctor-delivered lifestyle counseling combined with two smartphone apps can help people aged 60 and older who had a liver or kidney transplant eat healthier and be more active.
-
Long-term health of children born to mothers who had a solid organ transplant
This project will look for long-term heart, kidney, and immune system problems in people aged 16 and older who were born to mothers who had a kidney, liver, pancreas, heart, or lung transplant.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.