Managing bleeding during liver transplantation
Perioperative Hemostasis Management in Liver Transplantation
Société Française d'Anesthésie et de Réanimation · NCT06257407
This study looks at how to better manage bleeding during liver transplants by understanding what causes it and how much blood patients might need during the surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Société Française d'Anesthésie et de Réanimation (other) |
| Locations | 16 sites (Besançon and 15 other locations) |
| Trial ID | NCT06257407 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the management of hemostasis during liver transplantation, a procedure associated with significant bleeding risks. It aims to identify and analyze various risk factors that contribute to intraoperative bleeding and transfusion needs, which can occur at different phases of the surgery. By examining patient characteristics and surgical phases, the study seeks to improve predictive models for transfusion requirements, ultimately enhancing patient outcomes during liver transplantation.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and over who are undergoing liver transplantation.
Not a fit: Patients undergoing multi-organ transplantation or those not affiliated with a social security scheme may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better management strategies for bleeding during liver transplantation, reducing the need for transfusions and improving surgical outcomes.
How similar studies have performed: While there have been studies on hemostasis in liver transplantation, this approach focuses specifically on the intraoperative phases and may provide novel insights into transfusion management.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 or over * Liver transplant patient Exclusion Criteria: * Multi-organ transplantation * Protected populations: under guardianship or curatorship * Patients not affiliated to a social security scheme
Where this trial is running
Besançon and 15 other locations
- Chru Minjoz — Besançon, France (RECRUITING)
- CHU Estaing — Clermont, France (NOT_YET_RECRUITING)
- Hôpital Beaujon — Clichy, France (NOT_YET_RECRUITING)
- CHU Grenoble Alpes — Grenoble, France (NOT_YET_RECRUITING)
- CHU Claude Huriez — Lille, France (RECRUITING)
- Hôpital de la Croix-Rousse — Lyon, France (RECRUITING)
- CHU La Timone — Marseille, France (NOT_YET_RECRUITING)
- Hôpital St Eloi — Montpellier, France (NOT_YET_RECRUITING)
- Hôpital De L'Archet 2 — Nice, France (NOT_YET_RECRUITING)
- CHU Pitié-Salpêtrière — Paris, France (NOT_YET_RECRUITING)
- CHU Haut Levêque — Pessac, France (NOT_YET_RECRUITING)
- CHU Pontchaillou — Rennes, France (NOT_YET_RECRUITING)
- CHU Hautepierre — Strasbourg, France (NOT_YET_RECRUITING)
- CHU Toulouse Rangueil — Toulouse, France (NOT_YET_RECRUITING)
- CHU Tours — Tours, France (NOT_YET_RECRUITING)
- Hôpital Paul Brousse — Villejuif, France (RECRUITING)
Study contacts
- Principal investigator: WEISS, MD — Hôpital Beaujon
- Study coordinator: Emmanuel WEISS, MD
- Email: emmanuel.weiss@aphp.fr
- Phone: +33 1 40 87 58 81
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Liver Transplant, Complications