Magnetic stimulation treatment for fatigue after stroke
Neuromodulation for Rehabilitation of Post-Stroke Fatigue: An rTMS Pilot Study
This study is testing whether a type of magnetic treatment can help stroke survivors feel less tired and improve their overall well-being.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 34 Years to 80 Years |
| Sex | All |
| Sponsor | VA Office of Research and Development Federal |
| Locations | 1 site (Decatur, Georgia) |
| Trial ID | NCT05584124 on ClinicalTrials.gov |
What this trial studies
This trial investigates the use of repetitive transcranial magnetic stimulation (rTMS) as a treatment for individuals experiencing fatigue following a stroke. Fatigue is a prevalent issue that can hinder recovery and quality of life for stroke survivors. Participants will receive either active rTMS or a sham treatment, and their levels of fatigue, mood, and cognitive function will be assessed before and after the intervention. The goal is to determine if rTMS can effectively alleviate post-stroke fatigue and improve overall well-being.
Who should consider this trial
Good fit: Ideal candidates are adults aged 35 to 80 who are more than six months post-stroke and experience clinically significant fatigue.
Not a fit: Patients with contraindications to rTMS, such as certain neurological conditions or severe hypertension, may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly reduce fatigue in stroke survivors, enhancing their ability to engage in daily activities.
How similar studies have performed: Other studies have shown promising results with rTMS for various neurological conditions, suggesting potential efficacy for post-stroke fatigue.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 34 - 80 years of age * more than 6 months post-stroke * Clinically present fatigue Exclusion Criteria: * Contraindications to MRI/TMS/rTMS (e.g. implanted metal within the head, history of seizures) * Inability to follow simple three-step instructions * Diagnosed comorbid neurological conditions (e.g. multiple sclerosis, Parkinson's disease, moderate/severe TBI) * Pregnancy * strokes within stimulation sites * Pregnancy * Severe hypertension (resting SBP \> 200, DBP \> 120)
Where this trial is running
Decatur, Georgia
- Atlanta VA Medical and Rehab Center, Decatur, GA — Decatur, Georgia, United States (Recruiting)
Study contacts
- Principal investigator: John H Kindred — Atlanta VA Medical and Rehab Center, Decatur, GA
- Study coordinator: John H Kindred
- Email: John.Kindred1@va.gov
- Phone: (970) 426-9350
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.