Lung cancer screening using low-dose CT scans in women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of low-dose thoracic CT scans for lung cancer screening in women aged 50 to 74 with a significant smoking history. It will compare the performance of a single trained general radiologist reading the scans against double readings by expert radiologists. Additionally, the study will assess the role of artificial intelligence in aiding the detection of lung nodules. Participants will undergo baseline, 1-year, and 2-year follow-up scans to monitor for lung cancer signs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women aged from 50 to 74 years
* who had smoked at least 20 pack years and quit less than 15 years ago
* Had given their consent and accepted the need for a 2-year follow-up
* Affiliated to the social security system

Exclusion Criteria

* Presence of clinical symptoms suggesting malignancy (weight loss, hemoptysis) or ongoing infection (cough with fever)
* Evolving cancer
* History of lung cancer
* A 2-year follow-up not possible
* Chest CT scan performed within 2 years prior to inclusion

Where it's running

• Hôtel-Dieu
  Paris, France Recruiting

Study contacts

• Principal investigator: Marie-Pierre REVEL, PhD — Assistance Publique - Hôpitaux de Paris
• Study coordinator: Marie-Pierre REVEL, PhD
• Email: marie-pierre.revel@aphp.fr
• Phone: +33 1 42 34 79 10

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.