Clinical trial Recruiting at 1 site Interventional Ages 40 to 80

LSVT-LOUD therapy for Turkish-speaking people with Parkinson’s disease

Official title: The Effect of Lee Silverman Voice Therapy-LOUD (LVST-LOUD) Therapy Method on Voice and Speech Skills and Examination of Therapy Experiences in Turkish-Speaking Individuals With Parkinson's Disease

Run by Atlas University · NCT07730073 · Data updated 2026-11-12

A Turkish-speaking group with Parkinson’s will try the LSVT-LOUD voice therapy to see if it improves loudness and speech quality.

Quick facts

Study typeInterventional
Ages40 Years to 80 Years
SexAll
Enrollment24 (estimated)
SponsorAtlas University
Academic / other
Locations1 site (Kâğıthane, Istanbul)
StatusRecruiting
StartedFebruary 18, 2026
Main results expectedDecember 2026
Study endsFebruary 2027
Registry record updatedJuly 28, 2026
Trial IDNCT07730073 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are native Turkish speakers with idiopathic PD, Hoehn and Yahr stage I–III, aged 40–80, with reported voice/speech impairment and adequate cognitive function (MMSE ≥ 24).

Probably not a fit

Individuals with significant cognitive impairment, other major neurological conditions, or uncorrected hearing loss may receive less or no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial tests the LSVT-LOUD protocol in Turkish-speaking adults with idiopathic Parkinson’s disease. Participants undergo intensive, four-week, 60-minute therapy sessions four times per week, focusing on high-effort vocal production and progressive tasks from words to conversation. Outcomes include objective measures of loudness and speech intelligibility as well as participant-reported experiences. The study adapts the standard LSVT-LOUD method to Turkish language and cultural context. It aims to inform clinical use and broader adaptation of this therapy for Turkish speakers with PD.

Why it matters

Potential benefit: If successful, participants may experience clearer speech and improved communication in daily life.

How similar studies have gone: Prior LSVT-LOUD studies show benefit in improving voice and speech in PD, though language adaptations are less common; results are supportive but context-dependent.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Diagnosis: Patients with a confirmed diagnosis of Idiopathic Parkinson's Disease (Hoehn and Yahr stages I-III).

Age: Individuals aged 40-80 years.

Language: Native Turkish speakers.

Cognitive Status: Sufficient cognitive function to participate in therapy (e.g., Mini-Mental State Examination (MMSE) score ≥ 24).

Communication: Presence of voice or speech impairment (e.g., hypophonia, reduced intelligibility) as confirmed by a speech-language pathologist.

Stability: Stable medication regimen for at least 1 month prior to the study initiation.

Exclusion Criteria:

Neurological Comorbidities: Presence of other significant neurological disorders (e.g., stroke, traumatic brain injury, multiple sclerosis) or active voice disorders (e.g., vocal cord nodules, laryngeal cancer).

Hearing Impairment: Uncorrected hearing loss that would interfere with speech assessment or therapy.

Cognitive Impairment: Diagnosis of dementia or severe cognitive impairment that prevents participation in the intensive LSVT-LOUD protocol.

Recent Surgery: History of laryngeal surgery or deep brain stimulation (DBS) within the last 6 months.

Therapy History: Previous experience with LSVT-LOUD or intensive speech therapy within the past year.

Where it's running

  • Atlas University
    Kâğıthane, Istanbul, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.