Low-intensity laser therapy to boost immune response in children with pneumonia
Official title: Impact of Low Intensity Laser Therapy on Immune System Response Among Children With Pneumonia
Run by Badr University · NCT07552116 · Data updated 2026-11-12
This trial will test whether adding low-intensity laser therapy to breathing exercises and usual medical care helps immune markers and breathing in children with Down syndrome and pneumonia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 3 Years to 5 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Badr University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | April 6, 2026 |
| Main results expected | May 30, 2026 |
| Study ends | May 30, 2026 |
| Registry record updated | April 27, 2026 |
| Trial ID | NCT07552116 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children with Down syndrome experiencing a first episode of bronchopneumonia, roughly preschool age (mean ~3.7 years in the study), who can attend center-based therapy and do inspiratory muscle training are the intended candidates.
✕Probably not a fit
Children with other chronic chest diseases, recurrent or complicated pneumonia, older children or adults, or those unable to tolerate the procedures are unlikely to receive benefit from this specific protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Forty children with Down syndrome and bronchopneumonia were assigned to two equal groups; both groups received standard medical treatment and inspiratory muscle training with postural drainage, while one group also received low-intensity laser therapy. Treatments were delivered three times per week for one month. Blood markers (WBC, IgG, IgA, IgM) and respiratory measures (respiratory rate and oxygen saturation) were measured before and after the one-month program. The study compares changes in immune and respiratory outcomes between the laser-plus-exercise group and the exercise-only group.
Why it matters
Potential benefit: If successful, adding low-intensity laser therapy could improve immune markers and oxygenation and speed recovery in children with Down syndrome who have pneumonia.
How similar studies have gone: Previous small studies of low-level laser therapy for immune modulation show limited and mixed results, so using it for pneumonia in children with Down syndrome is relatively novel and not yet widely validated.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Dawn Syndrome children with pneumonia * Mean age of 3.73±1.82 year * Children were in the first attack of bronchopneumonia. Exclusion Criteria: * Other chest disease
Where it's running
-
Mona Mohamed Abdelkhalek
Cairo, Egypt Recruiting
Study contacts
- Principal investigator: Mona Mohamed Abdelkhalek, assistance prof — Badr University
- Study coordinator: Mona Mohamed Abdelkhalek, assistance professor
- Email: mona.abdelkhalek@buc.edu.eg
- Phone: 00201024056108
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.