Low-glycemic-index, high-fiber diet for women with PCOS in rural Yunnan

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective cohort in which women meeting Rotterdam criteria for PCOS will follow a culturally adapted low-GI, high-fiber dietary plan for six months while remaining in their usual communities. Investigators will track metabolic markers (including measures of insulin resistance), androgen levels, and menstrual cycle patterns, alongside measures of adherence and feasibility in a resource-limited setting. The intervention is tailored to local high-carbohydrate eating habits to balance nutritional goals and practicality. Outcomes will be used to generate evidence-based dietary guidance for long-term PCOS care in similar rural areas.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* PCOS diagnosis will follow the Rotterdam criteria (presence of two of the following three features: oligo-/anovulation, clinical/biochemical hyperandrogenism, and polycystic ovarian morphology, with exclusion of related disorders). Additional inclusion criteria comprise: body mass index (BMI) ≥24 kg/m² (Chinese obesity threshold), stable weight for at least 3 months prior to enrollment (±2 kg), willingness to maintain current physical activity levels throughout the study period, and residence within the designated study area for a minimum of 6 months.

Exclusion Criteria:

* pregnancy or lactation; type 1 diabetes or type 2 diabetes; thyroid dysfunction, hyperprolactinemia, congenital adrenal hyperplasia, Cushing's syndrome, androgen-secreting tumors, or other endocrine disorders affecting metabolism; use of hormonal contraceptives, insulin sensitizers, or anti-obesity medications within the past 3 months (e.g., metformin, GLP-1 receptor agonists, systemic corticosteroids, hormonal contraceptives, anti-androgens). Severe hepatic/renal/cardiovascular disease; gastrointestinal disorders incompatible with high-fiber diets; history of bariatric surgery; current participation in other dietary intervention programs; and individuals with cognitive impairment or language communication barriers who cannot comprehend the study procedures or provide informed consent. Participants will be required to maintain their habitual physical activity levels during the intervention period and must not initiate new weight-loss medications/supplements; any deviations will be documented as protocol violations

Where it's running

• Department of Gynaecology, Gengma People's Hospital
  Gengma County, Yunnan, China Recruiting
• Gengma People's Hospital
  Lincang, Yunnan, China Recruiting

Study contacts

• Study coordinator: Zhiqin Chen, Doctor
• Email: ptchen1@hotmail.com
• Phone: 86+13671686734

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.