Longitudinal study on aging and neurodegenerative diseases
DC Longitudinal Study on Aging and Specimen Bank
This study is trying to see if different tests can help find Alzheimer's and other brain diseases in people over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 45 Years and up |
| Sex | All |
| Sponsor | Georgetown University Academic / other |
| Locations | 1 site (Washington D.C., District of Columbia) |
| Trial ID | NCT03702907 on ClinicalTrials.gov |
What this trial studies
This observational study conducted by the Georgetown University Memory Disorders Program aims to assess the feasibility of various diagnostic tests for Alzheimer's disease, mild cognitive impairment, and other neurodegenerative diseases. Participants will undergo cognitive assessments, lifestyle questionnaires, and provide blood and cerebrospinal fluid specimens for biochemical and genetic testing. The study includes both a main study with a single visit and an optional longitudinal substudy involving annual follow-ups. The findings will not be shared with participants, focusing instead on the research aspect of diagnosis.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 45 and older, particularly those with a family history of neurodegenerative diseases.
Not a fit: Patients under 45 years of age will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the early diagnosis of Alzheimer's and other neurodegenerative diseases, leading to better management and treatment options.
How similar studies have performed: Other studies have shown promise in using biochemical and genetic testing for diagnosing neurodegenerative diseases, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 45 and older. * Subjects within the age range of 45-50 years old must have a first degree relative with a neurodegenerative disease. Exclusion Criteria: * Individuals under 45 years of age
Where this trial is running
Washington D.C., District of Columbia
- Georgetown University Memory Disorders Program — Washington D.C., District of Columbia, United States (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.