Clinical trial Recruiting at 1 site Observational Ages 45 and up

Longitudinal study on aging and neurodegenerative diseases

Official title: DC Longitudinal Study on Aging and Specimen Bank

Run by Georgetown University · NCT03702907 · Data updated 2026-11-12

This study is trying to see if different tests can help find Alzheimer's and other brain diseases in people over time.

Quick facts

Study typeObservational
Ages45 Years and up
SexAll
Enrollment1000 (estimated)
SponsorGeorgetown University
Academic / other
Locations1 site (Washington D.C., District of Columbia)
StatusRecruiting
StartedJanuary 1, 2007
Main results expectedJanuary 2027
Study endsJanuary 2027
Registry record updatedOctober 24, 2019
Trial IDNCT03702907 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 45 and older, particularly those with a family history of neurodegenerative diseases.

Probably not a fit

Patients under 45 years of age will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study conducted by the Georgetown University Memory Disorders Program aims to assess the feasibility of various diagnostic tests for Alzheimer's disease, mild cognitive impairment, and other neurodegenerative diseases. Participants will undergo cognitive assessments, lifestyle questionnaires, and provide blood and cerebrospinal fluid specimens for biochemical and genetic testing. The study includes both a main study with a single visit and an optional longitudinal substudy involving annual follow-ups. The findings will not be shared with participants, focusing instead on the research aspect of diagnosis.

Why it matters

Potential benefit: If successful, this study could enhance the early diagnosis of Alzheimer's and other neurodegenerative diseases, leading to better management and treatment options.

How similar studies have gone: Other studies have shown promise in using biochemical and genetic testing for diagnosing neurodegenerative diseases, indicating potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 45 and older.
* Subjects within the age range of 45-50 years old must have a first degree relative with a neurodegenerative disease.

Exclusion Criteria:

* Individuals under 45 years of age

Where it's running

  • Georgetown University Memory Disorders Program
    Washington D.C., District of Columbia, United States
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.