Long-term follow-up on childhood obstructive sleep apnea
An 18-year Follow-up Study on Obstructive Sleep Apnoea in a Population-based Cohort
This study is checking in on kids who had sleep apnea years ago to see how it has affected their health and development as they’ve grown up.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 248 (estimated) |
| Ages | 18 Years to 35 Years |
| Sex | All |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Trial ID | NCT05077748 on ClinicalTrials.gov |
What this trial studies
This observational study aims to follow up on a cohort of children diagnosed with obstructive sleep apnea (OSA) 18 years after their initial assessment. The research involves collecting data through questionnaires, anthropometric measurements, sleep studies, 24-hour ambulatory blood pressure monitoring, echocardiography, and neurocognitive assessments. Participants were originally recruited from primary schools and will be invited back to evaluate the long-term effects of OSA on their health. The study seeks to understand the epidemiology and natural history of OSA and its potential cardiovascular and neurocognitive complications.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals who participated in the original 2003 cohort of children diagnosed with obstructive sleep apnea.
Not a fit: Patients with neuromuscular diseases, severe chronic lung diseases, or craniofacial abnormalities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the long-term health outcomes of children with obstructive sleep apnea.
How similar studies have performed: Other studies have shown success in understanding the long-term impacts of obstructive sleep apnea in pediatric populations, making this approach both relevant and valuable.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: - Subjects participants from the 2003 cohort Exclusion Criteria: * Neuromuscular disease * Pathological central apnoea * Severe chronic lung disease with documented hypoxaemia or awake oxygen saturation \<92% * Chronic respiratory failure (unrelated to OSA) * Acquired upper airway disease/obstruction * Craniofacial abnormalities (e.g. secondary to trauma and malignancy) Other arrangement: * Subjects who have any respiratory illness within 2 weeks of the scheduled follow-up visit will have their assessment re-arranged until they have fully recovered. * Subjects taking medications that may affect sleep, upper airway patency or blood pressure (for example sedatives, stimulants, antihistamines, and cough medicine) within a week from recruitment will also be rescheduled to participate when they are free from medication use for at least 2 weeks. * Subjects with hypertension and are on anti-hypertensive therapy are allowed to continue on their medication and the information will be obtained and recorded during data collection.
Where this trial is running
Hong Kong
- Prince of Wales Hospital — Hong Kong, China (Recruiting)
Study contacts
- Study coordinator: Ching Ching, Kate Dr. CHAN
- Email: katechan@cuhk.edu.hk
- Phone: (852) 3505 2839
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.