Long-term follow-up for patients with COPD in Kingston

Kingston COPD Cohort

This study is trying to create a better way to follow up with people in Kingston who have COPD by collecting important health information to improve their care and treatment.

Quick facts

• Study type: Observational
• Enrollment: 400 (estimated)
• Ages: 40 Years to 85 Years
• Sex: All
• Sponsor: Queen's University (Academic / other)
• Locations: 1 site (Kingston, Ontario)
• Trial ID: NCT04200079 on ClinicalTrials.gov

What this trial studies

This observational cohort aims to establish a long-term multidimensional follow-up for patients diagnosed with Chronic Obstructive Pulmonary Disease (COPD) in Kingston, Ontario. The study will collect comprehensive clinical, laboratory, physiological, and radiological data from patients attending the Respirology clinic. Specific objectives include developing a straightforward follow-up protocol, hiring a research assistant, and setting up a database to facilitate ongoing patient management and research. The data gathered will help improve the understanding and treatment of COPD and its comorbidities.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 40-85 with a history of smoking and a diagnosis of COPD.

Not a fit: Patients with a life expectancy of less than three years or those in palliative care may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the management and treatment of COPD patients, leading to better health outcomes.

How similar studies have performed: Other studies focusing on long-term follow-up in COPD patients have shown promise, indicating that this approach is both relevant and potentially beneficial.

Eligibility criteria

Inclusion Criteria:

1. Patients ages between 40-85 years old.
2. Smoking history of at least 10 pack year history
3. Active of former smokers
4. Diagnosis of COPD according to the GOLD definition (4): post bronchodilator spirometry FEV1/FVC ≤0.70, including those with other associated respiratory diseases like asthma, bronchiectasis, stable lung cancer or Interstitial Lung Disease.
5. Ability to perform all study procedures (complete pulmonary function tests, six minute walking test (6MWT) and chest computed tomography) and provide/sign informed consent.

Exclusion Criteria:

1. Patients not willing to sign the consent form
2. Patients with a life expectancy of less than 3 yrs.
3. Patients in palliative care.
4. Patients with chronic airway obstruction ie: FEV1/FVC≤0.70 of other etiology and without a smoking history of less than 10 packs year history.
5. Patients unable ort not able to perform the pulmonary function test, the 6MWT or the chest CT.

Where this trial is running

Kingston, Ontario

• Khsc — Kingston, Ontario, Canada (Recruiting)

Study contacts

• Principal investigator: Juan P de Torres, MD — Queen's University
• Study coordinator: Juan P de Torres, MD

Conditions COPD; Emphysema