Clinical trial Recruiting at 1 site Observational Ages 18 and up

Long-term follow-up for liver transplant recipients and living donors

Official title: Longitudinal Follow-up and Health-Related Outcomes in Liver Transplant Recipients and Living Donors

Run by Second Affiliated Hospital, Zhejiang University, School of Medicine · NCT07301853 · Data updated 2026-11-12

This project will follow people who receive liver transplants and those who donate part of a liver to see if clinical factors predict complications and long-term health.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment9999 (estimated)
SponsorSecond Affiliated Hospital, Zhejiang University, School of Medicine
Academic / other
Locations1 site (Hangzhou, Zhejiang)
StatusRecruiting
StartedNovember 24, 2025
Main results expectedDecember 31, 2045
Study endsDecember 31, 2045
Registry record updatedDecember 24, 2025
Trial IDNCT07301853 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (age ≥18) undergoing liver transplantation or approved living donor hepatectomy at the study center who can provide informed consent and commit to long-term follow-up are ideal candidates.

Probably not a fit

Patients undergoing combined-organ transplants, those with severe mental illness or cognitive impairment that prevents follow-up, donors whose surgery is aborted, or anyone unable to comply with the long-term follow-up schedule are unlikely to receive benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective cohort will enroll adults who undergo liver transplantation or living donor hepatectomy at a single academic center in Hangzhou. Investigators will collect detailed clinical data and perform standardized long-term follow-up to document postoperative adverse events, functional outcomes, and quality of life for recipients and donors. The study aims to identify risk factors and to develop a specialized, individualized follow-up management system to optimize interventions. Participation requires informed consent and the ability to attend scheduled follow-up visits.

Why it matters

Potential benefit: If successful, the project could reduce complications and improve long-term health and quality of life for both transplant recipients and living donors through better-tailored follow-up and interventions.

How similar studies have gone: Similar transplant registries and longitudinal cohorts have helped identify risk factors and improve post-transplant care, although long-term, standardized follow-up for living donors is less consistently established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients undergoing liver transplantation or living donor hepatectomy at the study center (living donor should be approved by the hospital ethics committee for living organ donation);
2. Age 18 years or older;
3. Willing to participate in the long-term follow-up management program;
4. Signed informed consent form;

Exclusion Criteria:

1. Patients undergoing combined organ transplantation
2. Patients with severe mental illness or cognitive impairment who are unable to cooperate with follow-up assessments.
3. Donors whose surgery is aborted intraoperatively for any reason.
4. Unable or unwilling to comply with the long-term follow-up schedule.

Where it's running

  • The Second Affiliated Hospital Zhejiang University School of Medicine
    Hangzhou, Zhejiang, China
    Recruiting

Study contacts

  • Principal investigator: Wen Fang — Second Affiliated Hospital, Zhejiang University, School of Medicine
  • Study coordinator: Wen Fang
  • Email: wenfang@zju.edu.cn
  • Phone: 19705094680

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.