Long-term follow-up for liver transplant recipients and living donors
Longitudinal Follow-up and Health-Related Outcomes in Liver Transplant Recipients and Living Donors
This project will follow people who receive liver transplants and those who donate part of a liver to see if clinical factors predict complications and long-term health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 9999 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University Academic / other |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT07301853 on ClinicalTrials.gov |
What this trial studies
This prospective cohort will enroll adults who undergo liver transplantation or living donor hepatectomy at a single academic center in Hangzhou. Investigators will collect detailed clinical data and perform standardized long-term follow-up to document postoperative adverse events, functional outcomes, and quality of life for recipients and donors. The study aims to identify risk factors and to develop a specialized, individualized follow-up management system to optimize interventions. Participation requires informed consent and the ability to attend scheduled follow-up visits.
Who should consider this trial
Good fit: Adults (age ≥18) undergoing liver transplantation or approved living donor hepatectomy at the study center who can provide informed consent and commit to long-term follow-up are ideal candidates.
Not a fit: Patients undergoing combined-organ transplants, those with severe mental illness or cognitive impairment that prevents follow-up, donors whose surgery is aborted, or anyone unable to comply with the long-term follow-up schedule are unlikely to receive benefit from participation.
Why it matters
Potential benefit: If successful, the project could reduce complications and improve long-term health and quality of life for both transplant recipients and living donors through better-tailored follow-up and interventions.
How similar studies have performed: Similar transplant registries and longitudinal cohorts have helped identify risk factors and improve post-transplant care, although long-term, standardized follow-up for living donors is less consistently established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients undergoing liver transplantation or living donor hepatectomy at the study center (living donor should be approved by the hospital ethics committee for living organ donation); 2. Age 18 years or older; 3. Willing to participate in the long-term follow-up management program; 4. Signed informed consent form; Exclusion Criteria: 1. Patients undergoing combined organ transplantation 2. Patients with severe mental illness or cognitive impairment who are unable to cooperate with follow-up assessments. 3. Donors whose surgery is aborted intraoperatively for any reason. 4. Unable or unwilling to comply with the long-term follow-up schedule.
Where this trial is running
Hangzhou, Zhejiang
- The Second Affiliated Hospital Zhejiang University School of Medicine — Hangzhou, Zhejiang, China (Recruiting)
Study contacts
- Principal investigator: Wen Fang — Second Affiliated Hospital, School of Medicine, Zhejiang University
- Study coordinator: Wen Fang
- Email: wenfang@zju.edu.cn
- Phone: 19705094680
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.