Long-term follow-up for adults with metabolic syndrome and prediabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational cohort will enroll adults diagnosed with metabolic syndrome or prediabetes at National Taiwan University Hospital and collect routine clinical, laboratory, nutritional, and physical function data at regular intervals. Researchers will build a database of metabolic profiles and biomarkers to track disease progression, incident diabetes, cardiovascular events, and nutrition-related functional decline. Longitudinal analyses will examine how lifestyle behaviors, body composition, and laboratory markers relate to outcomes and identify prognostic determinants. The cohort will support improved risk stratification and provide data to inform prevention strategies and future interventional studies.

Why it matters

Who can join: the full rules

Inclusion Criteria

1. Adults aged 18 years or older.
2. Individuals clinically diagnosed by a physician as having metabolic syndrome (meeting at least three of the following five criteria) or prediabetes:

   (A) Waist circumference: ≥ 90 cm in men or ≥ 80 cm in women, or body mass index (BMI) ≥ 27 kg/m².

   (B) Fasting plasma glucose (AC): ≥ 100 mg/dL. (C) Blood pressure: Systolic blood pressure ≥ 130 mmHg or diastolic blood pressure ≥ 85 mmHg.

   (D) Triglycerides (TG): ≥ 150 mg/dL. (E) High-density lipoprotein cholesterol (HDL-C): \< 40 mg/dL in men or \< 50 mg/dL in women.
3. Individuals meeting the definition of prediabetes, defined as glycated hemoglobin (HbA1c) between 5.7% and 6.4%.
4. Participants who are willing to participate in the study and have signed written informed consent.
5. Participants who are able to complete basic physical examinations and assessment procedures.

Exclusion Criteria

1. Individuals unable to comprehend the study information or procedures.
2. Individuals unable to comply with the required assessments or study protocols.
3. Any other condition that, in the clinical judgment of the principal investigator, deems the individual unsuitable for participation.

Where it's running

• National Taiwan University Hospital
  Taipei, Zhongzheng Dist, Taiwan Recruiting

Study contacts

• Study coordinator: Chia-Wen Lu, Present Professor
• Email: biopsycosocial@gmail.com
• Phone: 886-2-23123456

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.