Long-term evaluation of surgical outcomes for rectal cancer treatment
Official title: Long-term Cohort Study of Mesorectal Excision for Rectal Cancer
Run by Kantonsspital Winterthur KSW · NCT05112016 · Data updated 2026-11-12
This study looks at how well surgery works for rectal cancer over time and how it affects patients' bowel and bladder function and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | Kantonsspital Winterthur KSW Academic / other |
| Locations | 1 site (Winterthur, Canton of Zurich) |
| Status | Recruiting |
| Started | January 1, 2007 |
| Main results expected | December 31, 2026 |
| Study ends | July 31, 2028 |
| Registry record updated | November 8, 2021 |
| Trial ID | NCT05112016 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include men and women over 18 years old who have been diagnosed with rectal cancer and have undergone mesorectal excision.
✕Probably not a fit
Patients under 18 years old or those who cannot provide informed consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This cohort study aims to evaluate and compare the surgical, oncological, and functional outcomes, as well as the quality of life, following total mesorectal excision for rectal cancer. It will analyze data from medical records and assess both retrospective outcomes from 2007-2016 and prospective outcomes from 2017-2026. The study will focus on bowel and urogenital function, along with quality of life metrics, measured at diagnosis and after stoma reversal. Variations in treatment approaches will also be examined for their impact on these outcomes.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into improving surgical techniques and patient quality of life after rectal cancer treatment.
How similar studies have gone: Other studies have shown success in evaluating surgical outcomes for rectal cancer, making this approach both relevant and potentially impactful.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and Women \>18 years * Patients with rectal cancer * Underwent mesorectal excision * Agreed to fill in a validated questionnaires before surgery and after stoma reversal * Informed consent Exclusion Criteria: * Age \< 18 * No informed consent (no general consent, no consent to use personal data for research purpose)
Where it's running
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Kantonsspital Winterthur
Winterthur, Canton of Zurich, Switzerland Recruiting
Study contacts
- Principal investigator: Michel Adamina, Prof/MD/MSc — Kantonsspital Winterthur KSW
- Study coordinator: Michel Adamina, Prof/MD/MSc
- Email: michel.adamina@ksw.ch
- Phone: +41522663376
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.