Long-term evaluation of surgical outcomes for rectal cancer treatment
Long-term Cohort Study of Mesorectal Excision for Rectal Cancer
This study looks at how well surgery works for rectal cancer over time and how it affects patients' bowel and bladder function and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Kantonsspital Winterthur KSW Academic / other |
| Locations | 1 site (Winterthur, Canton of Zurich) |
| Trial ID | NCT05112016 on ClinicalTrials.gov |
What this trial studies
This cohort study aims to evaluate and compare the surgical, oncological, and functional outcomes, as well as the quality of life, following total mesorectal excision for rectal cancer. It will analyze data from medical records and assess both retrospective outcomes from 2007-2016 and prospective outcomes from 2017-2026. The study will focus on bowel and urogenital function, along with quality of life metrics, measured at diagnosis and after stoma reversal. Variations in treatment approaches will also be examined for their impact on these outcomes.
Who should consider this trial
Good fit: Ideal candidates include men and women over 18 years old who have been diagnosed with rectal cancer and have undergone mesorectal excision.
Not a fit: Patients under 18 years old or those who cannot provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into improving surgical techniques and patient quality of life after rectal cancer treatment.
How similar studies have performed: Other studies have shown success in evaluating surgical outcomes for rectal cancer, making this approach both relevant and potentially impactful.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and Women \>18 years * Patients with rectal cancer * Underwent mesorectal excision * Agreed to fill in a validated questionnaires before surgery and after stoma reversal * Informed consent Exclusion Criteria: * Age \< 18 * No informed consent (no general consent, no consent to use personal data for research purpose)
Where this trial is running
Winterthur, Canton of Zurich
- Kantonsspital Winterthur — Winterthur, Canton of Zurich, Switzerland (Recruiting)
Study contacts
- Principal investigator: Michel Adamina, Prof/MD/MSc — Kantonsspital Winterthur KSW
- Study coordinator: Michel Adamina, Prof/MD/MSc
- Email: michel.adamina@ksw.ch
- Phone: +41522663376
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.