Clinical trial Recruiting at 1 site Observational Ages 18 and up

Long-term evaluation of surgical outcomes for rectal cancer treatment

Official title: Long-term Cohort Study of Mesorectal Excision for Rectal Cancer

Run by Kantonsspital Winterthur KSW · NCT05112016 · Data updated 2026-11-12

This study looks at how well surgery works for rectal cancer over time and how it affects patients' bowel and bladder function and quality of life.

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Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment250 (estimated)
SponsorKantonsspital Winterthur KSW
Academic / other
Locations1 site (Winterthur, Canton of Zurich)
StatusRecruiting
StartedJanuary 1, 2007
Main results expectedDecember 31, 2026
Study endsJuly 31, 2028
Registry record updatedNovember 8, 2021
Trial IDNCT05112016 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include men and women over 18 years old who have been diagnosed with rectal cancer and have undergone mesorectal excision.

Probably not a fit

Patients under 18 years old or those who cannot provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This cohort study aims to evaluate and compare the surgical, oncological, and functional outcomes, as well as the quality of life, following total mesorectal excision for rectal cancer. It will analyze data from medical records and assess both retrospective outcomes from 2007-2016 and prospective outcomes from 2017-2026. The study will focus on bowel and urogenital function, along with quality of life metrics, measured at diagnosis and after stoma reversal. Variations in treatment approaches will also be examined for their impact on these outcomes.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into improving surgical techniques and patient quality of life after rectal cancer treatment.

How similar studies have gone: Other studies have shown success in evaluating surgical outcomes for rectal cancer, making this approach both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Men and Women \>18 years
* Patients with rectal cancer
* Underwent mesorectal excision
* Agreed to fill in a validated questionnaires before surgery and after stoma reversal
* Informed consent

Exclusion Criteria:

* Age \< 18
* No informed consent (no general consent, no consent to use personal data for research purpose)

Where it's running

  • Kantonsspital Winterthur
    Winterthur, Canton of Zurich, Switzerland
    Recruiting

Study contacts

  • Principal investigator: Michel Adamina, Prof/MD/MSc — Kantonsspital Winterthur KSW
  • Study coordinator: Michel Adamina, Prof/MD/MSc
  • Email: michel.adamina@ksw.ch
  • Phone: +41522663376

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.