Clinical trial Recruiting at 1 site Observational Ages 19 and up

Long-term effects of tuberculosis on lung health in Korea

Official title: LIFE-TB ; Long-Term Impacts on Lung Health and Life After Tuberculosis in Korea

Run by Yonsei University · NCT06946784 · Data updated 2026-11-12

This study is trying to see how tuberculosis affects lung health and quality of life over time in adults who are being treated for or have had TB in Korea.

More Tuberculosis trials

Quick facts

Study typeObservational
Ages19 Years and up
SexAll
Enrollment360 (estimated)
SponsorYonsei University
Academic / other
Locations1 site (Seoul)
StatusRecruiting
StartedFebruary 25, 2025
Main results expectedDecember 31, 2031
Study endsDecember 31, 2031
Registry record updatedApril 27, 2025
Trial IDNCT06946784 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 19 and older who are currently being treated for pulmonary tuberculosis or have a history of treated TB.

Probably not a fit

Patients with extrapulmonary TB without lung involvement or those under 19 years of age may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The LIFE-TB study is a nationwide, multicenter observational cohort aimed at understanding the long-term impacts of tuberculosis on lung health and quality of life in adults. Participants, aged 19 and older, will be enrolled if they are currently undergoing treatment for pulmonary tuberculosis or have a history of treated TB. Over a five-year follow-up period, the study will collect data on respiratory symptoms, radiological changes, pulmonary function, and quality of life through various assessments. This research seeks to establish a comprehensive post-TB lung disease registry in Korea.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the long-term health consequences of tuberculosis, potentially leading to improved management strategies for post-TB lung disease.

How similar studies have gone: Other studies have shown success in understanding post-TB lung disease, but this specific nationwide registry approach is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥19 years
* Diagnosed with pulmonary TB and either initiating or undergoing treatment or history of treated pulmonary TB

Exclusion Criteria:

* Age \<19 years
* Extrapulmonary TB without lung involvement
* Refusal to provide informed consent

Where it's running

  • Department of Internal Medicine, Yonsei University College of Medicine Division of Pulmonology, Severance Hospital, Yonsei University Health System
    Seoul, South Korea
    Recruiting

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.