Long-term effects of tuberculosis on lung health in Korea
LIFE-TB ; Long-Term Impacts on Lung Health and Life After Tuberculosis in Korea
This study is trying to see how tuberculosis affects lung health and quality of life over time in adults who are being treated for or have had TB in Korea.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 360 (estimated) |
| Ages | 19 Years and up |
| Sex | All |
| Sponsor | Yonsei University Academic / other |
| Locations | 1 site (Seoul) |
| Trial ID | NCT06946784 on ClinicalTrials.gov |
What this trial studies
The LIFE-TB study is a nationwide, multicenter observational cohort aimed at understanding the long-term impacts of tuberculosis on lung health and quality of life in adults. Participants, aged 19 and older, will be enrolled if they are currently undergoing treatment for pulmonary tuberculosis or have a history of treated TB. Over a five-year follow-up period, the study will collect data on respiratory symptoms, radiological changes, pulmonary function, and quality of life through various assessments. This research seeks to establish a comprehensive post-TB lung disease registry in Korea.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 19 and older who are currently being treated for pulmonary tuberculosis or have a history of treated TB.
Not a fit: Patients with extrapulmonary TB without lung involvement or those under 19 years of age may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the long-term health consequences of tuberculosis, potentially leading to improved management strategies for post-TB lung disease.
How similar studies have performed: Other studies have shown success in understanding post-TB lung disease, but this specific nationwide registry approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥19 years * Diagnosed with pulmonary TB and either initiating or undergoing treatment or history of treated pulmonary TB Exclusion Criteria: * Age \<19 years * Extrapulmonary TB without lung involvement * Refusal to provide informed consent
Where this trial is running
Seoul
- Department of Internal Medicine, Yonsei University College of Medicine Division of Pulmonology, Severance Hospital, Yonsei University Health System — Seoul, South Korea (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.