Lifestyle changes plus nightly CPAP for glaucoma in people with sleep apnea

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Forty adults with high‑tension primary open‑angle glaucoma (intraocular pressure >21 mmHg), diagnosed obstructive sleep apnea, and obesity will be enrolled and split into two groups of 20 for three months. Both groups will use continuous positive airway pressure (CPAP) every night; one group will also follow lifestyle corrections consisting of a low‑calorie diet and three 40‑minute treadmill walking sessions per week. Intraocular pressure and other ophthalmic measures will be monitored over the three‑month intervention to compare outcomes between groups. The protocol focuses on short‑term IOP change as the primary outcome and feasibility of combining CPAP with structured lifestyle changes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Obstructive sleep apnea patients
* obese patients
* glaucoma (open angle form with ocular hyoertension)

Exclusion Criteria:

cardiac patients renal patients hepatic patients

Where it's running

• Cairo University
  Giza, Dokki, Egypt Recruiting

Study contacts

• Principal investigator: Ali MA Ismail, lecturer — Cairo University
• Study coordinator: Ali MA Ismail, lecturer
• Email: ali.mohamed@pt.cu.edu.eg
• Phone: 01005154209

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.