Life at 100.4: a social virtual reality education program for adolescents and young adults with cancer and their caregivers

Life at 100.4: An Immersive Social Virtual Reality Education Tool for Adolescent and Young Adult Cancer Patients and Caregivers

Not applicable Interventional Yale University · NCT07224204

This project will try a virtual reality program called Life at 100.4 to teach teens and young adults with new cancer diagnoses and their caregivers about febrile neutropenia.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment45 (estimated)
Ages13 Years to 39 Years
SexAll
SponsorYale University Academic / other
Drugs / interventionschemotherapy
Locations1 site (New Haven, Connecticut)
Trial IDNCT07224204 on ClinicalTrials.gov

What this trial studies

The team will design and beta test Life at 100.4, an immersive social VR education tool aimed at closing knowledge gaps about febrile neutropenia for patients and caregivers. Phase 1 includes interviews and focus groups with stakeholders to inform content and navigation. Phase 2 produces a VR prototype, and Phase 3 will pilot the tool with about five patient-caregiver-provider triads to measure feasibility and acceptability using validated instruments. The intervention targets people with new oncologic diagnoses who will receive chemotherapy and a central line.

Who should consider this trial

Good fit: Ideal candidates are adolescents and young adults newly diagnosed with a malignancy or bone marrow failure who plan to receive chemotherapy and a central line, together with a participating caregiver at Yale Pediatric Hematology/Oncology.

Not a fit: Patients with medical contraindications to virtual reality (for example, head wounds or a history of seizures triggered by flashing lights) or those not planning to receive chemotherapy are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, the program could help families recognize febrile neutropenia earlier, reduce delays to care, and lower related complications.

How similar studies have performed: Virtual reality has shown promise for patient education and procedural preparation in other settings, but the use of social VR specifically for febrile neutropenia education is novel and not previously well tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Newly diagnosed with a malignancy or bone marrow failure condition
* Planned to receive chemotherapy and receive a central line

Exclusion Criteria:

* Medical contraindication to virtual reality including head wounds and history of seizure with flashing lights
* No plan to receive chemotherapy

Where this trial is running

New Haven, Connecticut

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CancerAdolescent CancerYoung Adult CancerAdolescent Cancer Patients and CaregiversYoung Adult Cancer Patients and Caregivers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.