Life at 100.4: a social virtual reality education program for adolescents and young adults with cancer and their caregivers
Official title: Life at 100.4: An Immersive Social Virtual Reality Education Tool for Adolescent and Young Adult Cancer Patients and Caregivers
Run by Yale University · NCT07224204 · Data updated 2026-11-12
This project will try a virtual reality program called Life at 100.4 to teach teens and young adults with new cancer diagnoses and their caregivers about febrile neutropenia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 13 Years to 39 Years |
| Sex | All |
| Enrollment | 45 (estimated) |
| Sponsor | Yale University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (New Haven, Connecticut) |
| Status | Recruiting |
| Started | February 11, 2026 |
| Main results expected | April 2027 |
| Study ends | April 2027 |
| Registry record updated | February 25, 2026 |
| Trial ID | NCT07224204 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adolescents and young adults newly diagnosed with a malignancy or bone marrow failure who plan to receive chemotherapy and a central line, together with a participating caregiver at Yale Pediatric Hematology/Oncology.
✕Probably not a fit
Patients with medical contraindications to virtual reality (for example, head wounds or a history of seizures triggered by flashing lights) or those not planning to receive chemotherapy are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The team will design and beta test Life at 100.4, an immersive social VR education tool aimed at closing knowledge gaps about febrile neutropenia for patients and caregivers. Phase 1 includes interviews and focus groups with stakeholders to inform content and navigation. Phase 2 produces a VR prototype, and Phase 3 will pilot the tool with about five patient-caregiver-provider triads to measure feasibility and acceptability using validated instruments. The intervention targets people with new oncologic diagnoses who will receive chemotherapy and a central line.
Why it matters
Potential benefit: If successful, the program could help families recognize febrile neutropenia earlier, reduce delays to care, and lower related complications.
How similar studies have gone: Virtual reality has shown promise for patient education and procedural preparation in other settings, but the use of social VR specifically for febrile neutropenia education is novel and not previously well tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Newly diagnosed with a malignancy or bone marrow failure condition * Planned to receive chemotherapy and receive a central line Exclusion Criteria: * Medical contraindication to virtual reality including head wounds and history of seizure with flashing lights * No plan to receive chemotherapy
Where it's running
-
Pediatric Hematology/Oncology Clinic in Smilow Cancer Hospital
New Haven, Connecticut, United States Recruiting
Study contacts
- Principal investigator: Asher Marks, MD — Yale University
- Study coordinator: Asher Marks, MD
- Email: asher.marks@yale.edu
- Phone: 203-785-4640
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Child and Young Adult (CAYA) Cancer Outcomes Review
This project looks at past treatment results to see what affects outcomes for children and young adults (ages 0–21) with leukemia and other cancers treated at participating centers in low- and middle-income countries.
-
Comprehensive care needs for adolescents and young adults with cancer
See what education and support gaps adolescents and young adults with cancer have around exercise, sexual health, fertility, survivorship, finances, relationships, and clinical trials.
-
Mindset Moments program for young adult cancer survivors (ages 19–25)
This program will test whether eight weekly online group sessions plus daily 5-minute app activities can reduce distress and build resilience in young adult cancer survivors.
-
Exercise and lifestyle support for adolescents with cancer
This study is testing whether an exercise program and lifestyle support can help teenagers with cancer feel better during their treatment compared to standard care.
-
Yoga program for young adults with cancer
This study tests a yoga program for young adults with cancer to see if it can help improve their physical and mental well-being.
-
Gyrotonic exercise for elders with breast cancer and Behcet disease
We’re testing whether a gyrotonic exercise program helps older people who have both Behcet disease and breast cancer.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.