Left stellate ganglion block to reduce radial artery catheter problems during elective heart surgery
Effect of Stellate Ganglion Block on Arterial Catheterization Complications in Selected Group of Patients Undergoing Elective Cardiac Surgeries
NA · Ain Shams University · NCT07077824
This test will see if a left stellate ganglion block with bupivacaine reduces radial artery catheter complications and abnormal radial-to-femoral pressure differences in people having elective heart surgery who are expected to need long bypass times.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Ain Shams University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT07077824 on ClinicalTrials.gov |
What this trial studies
The study gives a left stellate ganglion block with bupivacaine around the time of arterial catheter placement for patients undergoing elective cardiac surgery and then monitors for radial artery complications and radial-to-femoral arterial pressure gradients after cardiopulmonary bypass. Participants are drawn from higher-risk surgical cases such as those with reduced left ventricular function (EF <35%), prolonged expected bypass time (>100 minutes), or moderate-to-severe pulmonary hypertension. Key outcomes include incidence of radial artery spasm, hematoma, occlusion/ischemia and the frequency/magnitude of post-bypass radial-to-femoral pressure gradients. Patients with contraindications such as coagulopathy, allergy to local anesthetic, glaucoma, prior stroke/TIA, contralateral phrenic nerve palsy, or BMI >35 are excluded.
Who should consider this trial
Good fit: Ideal candidates are adults having elective cardiac surgery with expected prolonged bypass times and risk factors like low EF or significant pulmonary hypertension who have no contraindications to a stellate ganglion block.
Not a fit: Patients unlikely to benefit include those not expected to need long bypass times, those who will not have radial arterial monitoring, or patients with contraindications such as coagulopathy, local anesthetic allergy, glaucoma, or contralateral phrenic nerve palsy.
Why it matters
Potential benefit: If successful, this approach could lower the rate of radial artery catheter complications and reduce misleading radial-to-femoral pressure differences, improving hemodynamic management around bypass.
How similar studies have performed: Some small studies and case reports show stellate ganglion block can increase upper-limb blood flow and reduce vasospasm, but high-quality evidence specifically preventing arterial catheter complications in cardiac surgery is limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * • Multiple procedures with expected prolonged bypass time (\>100 min) * EF\< 35% * Moderate or severe Pulmonary hypertension Exclusion Criteria: * • Patient not willing to participate in the study. * History of strokes / Transient ischaemic attacks * History of Glaucoma. * History of allergy to local anaesthetic drugs. * Pre-existing contralateral phrenic nerve palsy. * Patients with existing coagulopathy. * BMI \>35
Where this trial is running
Cairo
- faculty of medicine Ain Shams University — Cairo, Egypt (RECRUITING)
Study contacts
- Study coordinator: abdallah M soudi
- Email: Dr.soudi2014@med.asu.edu.eg
- Phone: +201111228925
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cardiac Surgery, stellate ganglion block, femoral radial gradient, arterial catheterization complications